SEC 13F Intelligence

Managers / Q2 2025 · view latest →

HighVista Strategies LLC

CIK 0001335325 · 200 CLARENDON STREET, 50TH FLOOR, BOSTON, MA, 02116 · 617-406-6500

Reported Value
$272M
Q2 2025
Positions
146
Filings on Record
30
2019–present window
Filed
Aug 14, 2025
original filing

Summary

Highvista Strategies LLC reported $272M in U.S.-listed holdings across 146 positions for Q2 2025.

Its largest position, DBC, represents 11.5% of the portfolio.

Compared with Q1 2025, the fund opened 29 new positions and exited 31.

Portfolio Metrics

Turnover
+23.7%
vs prior filed quarter
Top-10 Concentration
+27.3%
share of reported value
Largest Position
+11.5%
Invesco Db Commdy Indx Trck
New / Exited
29 / 31
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’18: $116MQ4 ’18Q1 ’19: $123MQ2 ’19: $195MQ3 ’19: $147MQ4 ’19: $132MQ4 ’19Q1 ’20: $108MQ2 ’20: $121MQ3 ’20: $137MQ4 ’20: $157MQ4 ’20Q1 ’21: $135MQ2 ’21: $141MQ3 ’21: $151MQ4 ’21: $126MQ4 ’21Q1 ’22: $157MQ2 ’22: $166MQ3 ’22: $175MQ4 ’22: $168MQ4 ’22Q1 ’23: $123MQ2 ’23: $219MQ3 ’23: $216MQ4 ’23: $276MQ4 ’23Q1 ’24: $280MQ2 ’24: $274MQ3 ’24: $290MQ4 ’24: $269MQ4 ’24Q1 ’25: $260MQ2 ’25: $272MQ3 ’25: $408MQ4 ’25: $388MQ4 ’25Q1 ’26: $362Mfilingsflow.com

Portfolio Composition

By security type
Common Stock: 75.7%ETP: 11.5%Other: 6.2%ADR: 6.2%REIT: 0.5%
  • Common Stock · 75.7% · $206M
  • ETP · 11.5% · $31M
  • Other · 6.2% · $17M
  • ADR · 6.2% · $17M
  • REIT · 0.5% · $1M

Quarter-over-Quarter Changes full breakdown →

vs Q1 2025 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
AMDADVANCED MICRO DEVICES INCNEW+15.4K15.4K+$2M$2M
TCE2CELLDEX THERAPEUTICS INC NEWNEW+106.6K106.6K+$2M$2M
FERGFERGUSON ENTERPRISES INCNEW+9.9K9.9K+$2M$2M
MLYSMINERALYS THERAPEUTICS INCNEW+150.1K150.1K+$2M$2M
LYFTLYFT INCNEW+125.8K125.8K+$2M$2M
CLFCLEVELAND-CLIFFS INC NEWNEW+255.6K255.6K+$2M$2M
SNDKSANDISK CORPNEW+39.6K39.6K+$2M$2M
ENQENTEGRIS INCNEW+20.9K20.9K+$2M$2M

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q2 2025

50 positions
Export to Excel
#IssuerClass% PortfolioValue ↓Shares
1DBCINVESCO DB COMMDY INDX TRCKhistory →UNIT11.51%$31M1.44M
2VRDNVIRIDIAN THERAPEUTICS INChistory →COM2.49%$7M484.6K
3AKXANSYS INChistory →COM2.21%$6M17.1K
4MSFTMICROSOFT CORPhistory →COM1.87%$5M10.3K
5MERUS N VCOM1.73%$5M89.8K
6JNPJUNIPER NETWORKS INChistory →COM1.68%$5M114.7K
7AMZNAMAZON COM INChistory →COM1.52%$4M18.9K
8HESHESS CORPhistory →COM1.47%$4M28.9K
9AMEDAMEDISYS INChistory →COM1.42%$4M39.3K
10NUVLNUVALENT INChistory →COM1.41%$4M50.5K
11AVGOBROADCOM INChistory →COM1.30%$4M12.8K
12WDCWESTERN DIGITAL CORPhistory →COM1.19%$3M50.6K
13AKROAKERO THERAPEUTICS INChistory →COM1.18%$3M60.0K
14PTGXPROTAGONIST THERAPEUTICS INChistory →COM1.17%$3M57.9K
15SEAGATE TECHNOLOGY HLDNGS PLORD SHS1.17%$3M22.1K
16CORZCORE SCIENTIFIC INC NEWhistory →COM1.13%$3M179.9K
17CRMSALESFORCE INChistory →COM1.12%$3M11.2K
18IMVTIMMUNOVANT INChistory →COM1.07%$3M182.8K
19BBIOBRIDGEBIO PHARMA INChistory →COM1.07%$3M67.5K
20X0M1XOMA ROYALTY CORPORATIONhistory →COM NEW1.06%$3M114.5K
21ELVNENLIVEN THERAPEUTICS INChistory →COM1.04%$3M141.5K
22PRAXPRAXIS PRECISION MEDICINES Ihistory →COM NEW1.04%$3M67.3K
23VRNAVERONA PHARMA PLChistory →SPONSORED ADS1.00%$3M28.9K
24CEGCONSTELLATION ENERGY CORPCOM0.98%$3M8.3K
25XPOXPO INCCOM0.98%$3M21.1K
26INTUINTUITCOM0.94%$3M3.3K
27RVMDREVOLUTION MEDICINES INCCOM0.92%$3M68.0K
28NVDANVIDIA CORPORATIONCOM0.91%$2M15.7K
29PWRQUANTA SVCS INCCOM0.89%$2M6.4K
30ACLXGBXARCELLX INCCOMMON STOCK0.86%$2M35.7K
31AGIOAGIOS PHARMACEUTICALS INCCOM0.86%$2M70.1K
32METAMETA PLATFORMS INCCL A0.84%$2M3.1K
33VVISA INCCOM CL A0.84%$2M6.4K
34CYTKCYTOKINETICS INCCOM NEW0.83%$2M68.7K
35MAMASTERCARD INCORPORATEDCL A0.83%$2M4.0K
36MMM3M COCOM0.81%$2M14.4K
37AMDADVANCED MICRO DEVICES INCCOM0.80%$2M15.4K
38TCE2CELLDEX THERAPEUTICS INC NEWCOM NEW0.80%$2M106.6K
39FERGFERGUSON ENTERPRISES INCCOMMON STOCK NEW0.79%$2M9.9K
40GEVGE VERNOVA INCCOM0.78%$2M4.0K
41BKNGBOOKING HOLDINGS INCCOM0.76%$2M357
42COGTCOGENT BIOSCIENCES INCCOM0.75%$2M283.2K
43MLYSMINERALYS THERAPEUTICS INCCOM0.75%$2M150.1K
44SNPSSYNOPSYS INCCOM0.73%$2M3.9K
45LYFTLYFT INCCL A COM0.73%$2M125.8K
46APGEAPOGEE THERAPEUTICS INCCOM0.72%$2M45.1K
47CLFCLEVELAND-CLIFFS INC NEWCOM0.71%$2M255.6K
48APHAMPHENOL CORP NEWCL A0.69%$2M19.0K
49MTZMASTEC INCCOM0.69%$2M11.0K
50QXOQXO INCCOM NEW0.67%$2M84.5K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$362M156May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$388M145Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$408M148Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$272M146Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$260M148May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$269M137Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$290M142Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$274M138Aug 14, 202413F-HRchanges · EDGAR ↗
Q1 2024$280M131May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$276M126Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$216M132Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$219M134Aug 14, 202313F-HRchanges · EDGAR ↗
Q1 2023$123M108May 15, 202313F-HRchanges · EDGAR ↗
Q4 2022$168M105Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$175M113Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$166M110Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$157M86May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$126M69Feb 14, 202213F-HRchanges · EDGAR ↗
Q3 2021$151M127Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021$141M116Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$135M125May 17, 202113F-HRchanges · EDGAR ↗
Q4 2020$157M117Feb 16, 202113F-HRchanges · EDGAR ↗
Q3 2020$137M113Nov 16, 202013F-HRchanges · EDGAR ↗
Q2 2020$121M100Aug 14, 202013F-HRchanges · EDGAR ↗
Q1 2020$108M65May 15, 202013F-HRchanges · EDGAR ↗
Q4 2019$132M119Feb 14, 202013F-HRchanges · EDGAR ↗
Q3 2019$147M126Nov 14, 201913F-HRchanges · EDGAR ↗
Q2 2019$195M108Aug 14, 201913F-HRchanges · EDGAR ↗
Q1 2019$123M112May 15, 201913F-HRchanges · EDGAR ↗
Q4 2018$116M113Feb 14, 201913F-HRchanges · EDGAR ↗

Other Included Managers

This filing reports holdings on behalf of 1 additional manager.

  • HighVista Private Capital Management LLC

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.