SEC 13F Intelligence

Managers / Q1 2025 · view latest →

HighVista Strategies LLC

CIK 0001335325 · 200 CLARENDON STREET, 50TH FLOOR, BOSTON, MA, 02116 · 617-406-6500

Reported Value
$260M
Q1 2025
Positions
148
Filings on Record
30
2019–present window
Filed
May 15, 2025
original filing

Summary

Highvista Strategies LLC reported $260M in U.S.-listed holdings across 148 positions for Q1 2025.

Its largest position, DBC, represents 12.5% of the portfolio.

Compared with Q4 2024, the fund opened 35 new positions and exited 24.

Portfolio Metrics

Turnover
+23.3%
vs prior filed quarter
Top-10 Concentration
+25.8%
share of reported value
Largest Position
+12.5%
Invesco Db Commdy Indx Trck
New / Exited
35 / 24
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded, with multiple share classes and repeated sub-manager rows for the same issuer combined into one position — the same rule the holdings table uses by default. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’18: $116MQ4 ’18Q1 ’19: $123MQ2 ’19: $195MQ3 ’19: $147MQ4 ’19: $132MQ4 ’19Q1 ’20: $108MQ2 ’20: $121MQ3 ’20: $137MQ4 ’20: $157MQ4 ’20Q1 ’21: $135MQ2 ’21: $141MQ3 ’21: $151MQ4 ’21: $126MQ4 ’21Q1 ’22: $157MQ2 ’22: $166MQ3 ’22: $175MQ4 ’22: $168MQ4 ’22Q1 ’23: $123MQ2 ’23: $219MQ3 ’23: $216MQ4 ’23: $276MQ4 ’23Q1 ’24: $280MQ2 ’24: $274MQ3 ’24: $290MQ4 ’24: $269MQ4 ’24Q1 ’25: $260MQ2 ’25: $272MQ3 ’25: $408MQ4 ’25: $388MQ4 ’25Q1 ’26: $362Mfilingsflow.com

Portfolio Composition

By security type
Common Stock: 80.1%ETP: 12.5%ADR: 6.0%Other: 1.5%
  • Common Stock · 80.1% · $208M
  • ETP · 12.5% · $32M
  • ADR · 6.0% · $15M
  • Other · 1.5% · $4M

Quarter-over-Quarter Changes full breakdown →

vs Q4 2024 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
PWRQUANTA SVCS INCNEW+8.1K8.1K+$2M$2M
BHCBAUSCH HEALTH COS INCNEW+217.6K217.6K+$2M$2M
MAMASTERCARD INCORPORATEDNEW+3.7K3.7K+$2M$2M
MMM3M CONEW+13.5K13.5K+$2M$2M
MTZMASTEC INCNEW+16.3K16.3K+$2M$2M
IMVTIMMUNOVANT INCNEW+95.6K95.6K+$2M$2M
NATLNCR ATLEOS CORPORATIONNEW+61.9K61.9K+$2M$2M
LKQLKQ CORPNEW+36.7K36.7K+$2M$2M

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q1 2025

148 positions
Export to Excel
#IssuerClass% PortfolioValue ↓Shares
1DBCINVESCO DB COMMDY INDX TRCKhistory →UNIT12.45%$32M1.44M
2HESHESS CORPhistory →COM1.78%$5M28.9K
3JNPJUNIPER NETWORKS INChistory →COM1.60%$4M114.7K
4ACIALBERTSONS COS INChistory →COMMON STOCK1.60%$4M188.8K
5AKXANSYS INChistory →COM1.56%$4M12.8K
6PTGXPROTAGONIST THERAPEUTICS INChistory →COM1.46%$4M78.5K
7MSFTMICROSOFT CORPhistory →COM1.41%$4M9.8K
8AMEDAMEDISYS INChistory →COM1.40%$4M39.3K
9AMZNAMAZON COM INChistory →COM1.37%$4M18.7K
10ARCELLX INCCOMMON STOCK1.20%$3M47.5K
11DVAXDYNAVAX TECHNOLOGIES CORPhistory →COM NEW1.18%$3M235.2K
12SPRINGWORKS THERAPEUTICS INCCOM1.17%$3M68.8K
13LQDALIQUIDIA CORPORATIONhistory →COM NEW1.16%$3M203.5K
14GEVGE VERNOVA INChistory →COM1.15%$3M9.8K
15XPOXPO INChistory →COM1.11%$3M26.9K
16NUVLNUVALENT INChistory →COM1.09%$3M39.9K
17AVGOBROADCOM INChistory →COM1.03%$3M15.9K
18RVMDREVOLUTION MEDICINES INChistory →COM1.00%$3M73.8K
19AXSMAXSOME THERAPEUTICS INCCOM0.97%$3M21.5K
20CRMSALESFORCE INCCOM0.96%$2M9.3K
21VRDNVIRIDIAN THERAPEUTICS INCCOM0.94%$2M180.6K
22APELLIS PHARMACEUTICALS INCCOM0.92%$2M108.7K
23INTUINTUITCOM0.91%$2M3.9K
24ALKSALKERMES PLCSHS0.90%$2M70.8K
25MERUS N VCOM0.89%$2M55.0K
26X0M1XOMA ROYALTY CORPORATIONCOM NEW0.88%$2M114.5K
27XENEXENON PHARMACEUTICALS INCCOM0.86%$2M66.8K
28ELVNENLIVEN THERAPEUTICS INCCOM0.85%$2M112.5K
29GHGUARDANT HEALTH INCCOM0.85%$2M51.7K
30VVISA INCCOM CL A0.83%$2M6.1K
31GOOGALPHABET INCCAP STK CL C0.81%$2M13.4K
32HPEHEWLETT PACKARD ENTERPRISE CCOM0.79%$2M133.5K
33PWRQUANTA SVCS INCCOM0.79%$2M8.1K
34CEGCONSTELLATION ENERGY CORPCOM0.78%$2M10.1K
35BHCBAUSCH HEALTH COS INCCOM0.78%$2M217.6K
36MAMASTERCARD INCORPORATEDCL A0.78%$2M3.7K
37JANXJANUX THERAPEUTICS INCCOM0.78%$2M74.6K
38EWTXEDGEWISE THERAPEUTICS INCCOM0.77%$2M91.2K
39CSCOCISCO SYS INCCOM0.77%$2M32.2K
40MMM3M COCOM0.76%$2M13.5K
41STXSEAGATE TECHNOLOGY HLDNGS PLORD SHS0.75%$2M23.0K
42WDCWESTERN DIGITAL CORPCOM0.75%$2M48.3K
43PMPHILIP MORRIS INTL INCCOM0.74%$2M12.1K
44MTZMASTEC INCCOM0.73%$2M16.3K
45ARGXARGENX SESPONSORED ADR0.73%$2M3.2K
46GEHCGE HEALTHCARE TECHNOLOGIES ICOMMON STOCK0.72%$2M23.2K
47RYTMRHYTHM PHARMACEUTICALS INCCOM0.72%$2M35.0K
48METAMETA PLATFORMS INCCL A0.71%$2M3.2K
49STZCONSTELLATION BRANDS INCCL A0.70%$2M9.9K
50RCLROYAL CARIBBEAN GROUPCOM0.70%$2M8.8K
51CYTKCYTOKINETICS INCCOM NEW0.69%$2M44.7K
52MLTXMOONLAKE IMMUNOTHERAPEUTICSCLASS A ORD0.66%$2M43.5K
53COGTCOGENT BIOSCIENCES INCCOM0.65%$2M279.7K
54KNSAKINIKSA PHARMACEUTICALS INTLORD SHS CL A0.64%$2M74.6K
55BKNGBOOKING HOLDINGS INCCOM0.63%$2M357
56INSMINSMED INCCOM PAR $.010.63%$2M21.4K
57IMVTIMMUNOVANT INCCOM0.63%$2M95.6K
58NATLNCR ATLEOS CORPORATIONCOM SHS0.63%$2M61.9K
59APGEAPOGEE THERAPEUTICS INCCOM0.62%$2M43.2K
60BBIOBRIDGEBIO PHARMA INCCOM0.62%$2M46.5K
61AVIDITY BIOSCIENCES INCCOM0.62%$2M54.2K
62NVDANVIDIA CORPORATIONCOM0.61%$2M14.6K
63PTCPTC INCCOM0.60%$2M10.1K
64LKQLKQ CORPCOM0.60%$2M36.7K
65TLNTALEN ENERGY CORPCOM0.59%$2M7.7K
66SYRESPYRE THERAPEUTICS INCCOM NEW0.59%$2M95.2K
67AGXARGAN INCCOM0.59%$2M11.7K
68OFIXORTHOFIX MED INCCOM0.58%$2M92.9K
69APHAMPHENOL CORP NEWCL A0.58%$2M22.9K
70PRAXPRAXIS PRECISION MEDICINES ICOM NEW0.57%$1M39.3K
71TSMTAIWAN SEMICONDUCTOR MFG LTDSPONSORED ADS0.57%$1M8.9K
72CNXCNX RES CORPCOM0.57%$1M46.7K
73CRHCRH PLCORD0.57%$1M16.7K
74CIENCIENA CORPCOM NEW0.57%$1M24.3K
75CORZCORE SCIENTIFIC INC NEWCOM0.56%$1M199.1K
76ELVELEVANCE HEALTH INCCOM0.55%$1M3.3K
77BNBROOKFIELD CORPCL A LTD VT SH0.55%$1M27.2K
78EYENATIONAL VISION HLDGS INCCOM0.55%$1M111.3K
79PGRPROGRESSIVE CORPCOM0.55%$1M5.0K
80TKOTKO GROUP HOLDINGS INCCL A0.54%$1M9.2K
81QXOQXO INCCOM NEW0.54%$1M103.5K
82UALUNITED AIRLS HLDGS INCCOM0.54%$1M20.2K
83SESEA LTDSPONSORD ADS0.54%$1M10.6K
84QSRRESTAURANT BRANDS INTL INCCOM0.52%$1M20.3K
85PFSIPENNYMAC FINL SVCS INC NEWCOM0.52%$1M13.4K
86DALDELTA AIR LINES INC DELCOM NEW0.52%$1M30.8K
87AALAMERICAN AIRLS GROUP INCCOM0.51%$1M126.1K
88SNPSSYNOPSYS INCCOM0.51%$1M3.1K
89WDAYWORKDAY INCCL A0.50%$1M5.6K
90RXORXO INCCOMMON STOCK0.50%$1M68.4K
91DUOLDUOLINGO INCCL A COM0.50%$1M4.2K
92AGIOAGIOS PHARMACEUTICALS INCCOM0.50%$1M44.1K
93ONON SEMICONDUCTOR CORPCOM0.49%$1M31.4K
94BVNCOMPANIA DE MINAS BUENAVENTUSPONSORED ADR0.49%$1M80.6K
95VERAVERA THERAPEUTICS INCCL A0.48%$1M52.2K
96PCVXVAXCYTE INCCOM0.48%$1M33.1K
97MRVLMARVELL TECHNOLOGY INCCOM0.48%$1M20.2K
98IBNICICI BANK LIMITEDADR0.47%$1M38.7K
99HDBHDFC BANK LTDSPONSORED ADS0.47%$1M18.2K
100MAGNMAGNERA CORPCOM SHS0.47%$1M66.6K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$362M156May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$388M145Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$408M148Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$272M146Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$260M148May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$269M137Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$290M142Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$274M138Aug 14, 202413F-HRchanges · EDGAR ↗
Q1 2024$280M131May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$276M126Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$216M132Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$219M134Aug 14, 202313F-HRchanges · EDGAR ↗
Q1 2023$123M108May 15, 202313F-HRchanges · EDGAR ↗
Q4 2022$168M105Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$175M113Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$166M110Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$157M86May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$126M69Feb 14, 202213F-HRchanges · EDGAR ↗
Q3 2021$151M127Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021$141M116Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$135M125May 17, 202113F-HRchanges · EDGAR ↗
Q4 2020$157M117Feb 16, 202113F-HRchanges · EDGAR ↗
Q3 2020$137M113Nov 16, 202013F-HRchanges · EDGAR ↗
Q2 2020$121M100Aug 14, 202013F-HRchanges · EDGAR ↗
Q1 2020$108M65May 15, 202013F-HRchanges · EDGAR ↗
Q4 2019$132M119Feb 14, 202013F-HRchanges · EDGAR ↗
Q3 2019$147M126Nov 14, 201913F-HRchanges · EDGAR ↗
Q2 2019$195M108Aug 14, 201913F-HRchanges · EDGAR ↗
Q1 2019$123M112May 15, 201913F-HRchanges · EDGAR ↗
Q4 2018$116M113Feb 14, 201913F-HRchanges · EDGAR ↗

Other Included Managers

This filing reports holdings on behalf of 1 additional manager.

  • HighVista Private Capital Management LLC

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.