SEC 13F Intelligence

Managers / Q1 2021 · view latest →

HighVista Strategies LLC

CIK 0001335325 · 200 CLARENDON STREET, 50TH FLOOR, BOSTON, MA, 02116 · 617-406-6500

Reported Value
$135M
Q1 2021
Positions
125
Filings on Record
30
2019–present window
Filed
May 17, 2021
original filing

Summary

Highvista Strategies LLC reported $135M in U.S.-listed holdings across 125 positions for Q1 2021.

The portfolio is heavily concentrated: DELL alone accounts for 23.3% of reported value.

Compared with Q4 2020, the fund opened 39 new positions and exited 31.

Portfolio Metrics

Turnover
+23.2%
vs prior filed quarter
Top-10 Concentration
+56.4%
share of reported value
Largest Position
+23.3%
Dell Technologies
New / Exited
39 / 31
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded, with multiple share classes and repeated sub-manager rows for the same issuer combined into one position — the same rule the holdings table uses by default. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’18: $116MQ4 ’18Q1 ’19: $123MQ2 ’19: $195MQ3 ’19: $147MQ4 ’19: $132MQ4 ’19Q1 ’20: $108MQ2 ’20: $121MQ3 ’20: $137MQ4 ’20: $157MQ4 ’20Q1 ’21: $135MQ2 ’21: $141MQ3 ’21: $151MQ4 ’21: $126MQ4 ’21Q1 ’22: $157MQ2 ’22: $166MQ3 ’22: $175MQ4 ’22: $168MQ4 ’22Q1 ’23: $123MQ2 ’23: $219MQ3 ’23: $216MQ4 ’23: $276MQ4 ’23Q1 ’24: $280MQ2 ’24: $274MQ3 ’24: $290MQ4 ’24: $269MQ4 ’24Q1 ’25: $260MQ2 ’25: $272MQ3 ’25: $408MQ4 ’25: $388MQ4 ’25Q1 ’26: $362Mfilingsflow.com

Portfolio Composition

By security type
Common Stock: 72.0%ADR: 12.3%Other: 11.7%ETP: 4.0%REIT: 0.1%
  • Common Stock · 72.0% · $97M
  • ADR · 12.3% · $16M
  • Other · 11.7% · $16M
  • ETP · 4.0% · $5M
  • REIT · 0.1% · $100,000

Quarter-over-Quarter Changes full breakdown →

vs Q4 2020 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
MSD ACQUISITION CORPNEW+500.0K500.0K+$5M$5M
RPREALPAGE INCNEW+38.6K38.6K+$3M$3M
ALXNALEXION PHARMACEUTICALS INCNEW+21.5K21.5K+$3M$3M
WORKSLACK TECHNOLOGIES INCNEW+80.6K80.6K+$3M$3M
ATHMAUTOHOME INCNEW+14.9K14.9K+$1M$1M
YUMCYUM CHINA HLDGS INCNEW+17.1K17.1K+$1M$1M
CURIS INCNEW+73.7K73.7K+$835,000$835,000
HORIZON THERAPEUTICS PUB LNEW+8.6K8.6K+$790,000$790,000

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q1 2021

124 positions
#IssuerClass% PortfolioValueShares
1DELLDELL TECHNOLOGIES INChistory →CL C23.28%$31M355.4K
2WTWWILLIS TOWERS WATSON PLC LTDhistory →SHS6.98%$9M41.1K
3BABAALIBABA GROUP HLDG LTDhistory →SPONSORED ADS5.75%$8M34.1K
4MSD ACQUISITION CORPUNIT 03/25/20263.77%$5M500.0K
5SMINISHARES TRMSCI INDIA SM CP · MSCI INDIA ETF3.46%$5M102.4K
6MXIMMAXIM INTEGRATED PRODS INChistory →COM2.89%$4M42.6K
7IPHIINPHI CORPhistory →COM2.86%$4M21.5K
8RPREALPAGE INChistory →COM2.50%$3M38.6K
9ALXNALEXION PHARMACEUTICALS INChistory →COM2.45%$3M21.5K
10WORKSLACK TECHNOLOGIES INChistory →COM CL A2.43%$3M80.6K
11XILINX INCCOM2.23%$3M24.2K
12SOGOU INCADR REPSTG A2.02%$3M360.0K
13DOUYU INTL HLDGS LTDSPONSORED ADS1.93%$3M249.6K
14GNWGENWORTH FINL INChistory →COM CL A1.43%$2M578.0K
15GRUBHUB INCCOM1.24%$2M27.9K
16ATHMAUTOHOME INChistory →SP ADS RP CL A1.03%$1M14.9K
17MGNXMACROGENICS INCCOM0.90%$1M38.2K
18TSMTAIWAN SEMICONDUCTOR MFG LTDSPONSORED ADS0.88%$1M10.0K
19BIDUBAIDU INCSPON ADR REP A0.77%$1M4.8K
20YUMCYUM CHINA HLDGS INCCOM0.75%$1M17.1K
21SUTRO BIOPHARMA INCCOM0.66%$887,00039.0K
22NEOLEUKIN THERAPEUTICS INCCOM0.65%$877,00071.2K
23IVERIC BIO INCCOM0.65%$872,000141.1K
24KURAKURA ONCOLOGY INCCOM0.63%$854,00030.2K
25AVADEL PHARMACEUTICALS PLCSPONSORED ADR0.62%$841,00093.1K
26CURIS INCCOM NEW0.62%$835,00073.7K
27HORIZON THERAPEUTICS PUB LSHS0.59%$790,0008.6K
28KRONOS BIO INCCOM0.59%$789,00026.9K
29RVMDREVOLUTION MEDICINES INCCOM0.58%$780,00017.0K
30SNDXSYNDAX PHARMACEUTICALS INCCOM0.58%$779,00034.9K
31ONCBEIGENE LTDSPONSORED ADR0.58%$777,0002.2K
32SAGE THERAPEUTICS INCCOM0.56%$757,00010.1K
33ARENA PHARMACEUTICALS INCCOM NEW0.55%$739,00010.7K
34MIRATI THERAPEUTICS INCCOM0.54%$731,0004.3K
35SPRINGWORKS THERAPEUTICS INCCOM0.53%$711,0009.7K
36TREURTRILLIUM THERAPEUTICS INCCOM NEW0.53%$711,00066.2K
37ASNDASCENDIS PHARMA A/SSPONSORED ADR0.53%$709,0005.5K
38DBCINVESCO DB COMMDY INDX TRCKUNIT0.52%$704,00042.4K
39AVIDITY BIOSCIENCES INCCOM0.51%$693,00031.8K
40PMVPPMV PHARMACEUTICALS INCCOM0.51%$687,00020.9K
41IGM BIOSCIENCES INCCOM0.51%$684,0008.9K
42TARSTARSUS PHARMACEUTICALS INCCOM0.51%$680,00021.1K
43CLDXCELLDEX THERAPEUTICS INC NEWCOM NEW0.50%$678,00032.9K
44ITEOS THERAPEUTICS INCCOM0.50%$677,00019.8K
45ZYMEWORKS INCCOM0.49%$663,00021.0K
46AXSMAXSOME THERAPEUTICS INCCOM0.49%$660,00011.7K
47CHEMOCENTRYX INCCOM0.49%$657,00012.8K
48CCCCC4 THERAPEUTICS INCCOM STK0.48%$651,00017.6K
49ARGXARGENX SESPONSORED ADR0.48%$649,0002.4K
50BDTXBLACK DIAMOND THERAPEUTICS ICOM0.48%$649,00026.8K
51ALTALTIMMUNE INCCOM NEW0.48%$648,00045.9K
52ADVERUM BIOTECHNOLOGIES INCCOM0.48%$640,00064.9K
53RCKTROCKET PHARMACEUTICALS INCCOM0.47%$636,00014.3K
54TVTXTRAVERE THERAPEUTICS INCCOM0.46%$615,00024.6K
55SPRYSILVERBACK THERAPEUTICS INCCOM0.46%$614,00014.1K
56INVITAE CORPCOM0.46%$613,00016.0K
57NVAXNOVAVAX INCCOM NEW0.45%$606,0003.3K
58NRIXNURIX THERAPEUTICS INCCOM0.44%$598,00019.2K
59ATHIRA PHARMA INCCOM0.44%$590,00032.1K
60RLAYRELAY THERAPEUTICS INCCOM0.43%$583,00016.9K
61FORMA THERAPEUTICS HLDGS INCSHS0.43%$578,00020.6K
62IOVAIOVANCE BIOTHERAPEUTICS INCCOM0.43%$575,00018.2K
63ORICORIC PHARMACEUTICALS INCCOM0.41%$547,00022.3K
64CNSTCONSTELLATION PHARMCETICLS ICOM0.40%$544,00023.3K
65KYMRKYMERA THERAPEUTICS INCCOM0.40%$542,00013.9K
66STOKSTOKE THERAPEUTICS INCCOM0.40%$532,00013.7K
67RYTMRHYTHM PHARMACEUTICALS INCCOM0.39%$528,00024.8K
68ATRECA INCCL A COM0.39%$526,00034.3K
69SOLID BIOSCIENCES INCCOM0.38%$506,00091.6K
70NKTXNKARTA INCCOM0.36%$491,00014.9K
71OLMAOLEMA PHARMACEUTICALS INCCOM0.36%$480,00014.5K
72ACADACADIA PHARMACEUTICALS INCCOM0.32%$428,00016.6K
73NVONOVO-NORDISK A SADR0.26%$345,0005.1K
74MOBILE TELESYSTEMS PJSCSPONSORED ADR0.25%$343,00041.1K
75CHKPCHECK POINT SOFTWARE TECH LTORD0.25%$332,0003.0K
76VRNAVERONA PHARMA PLCSPONSORED ADS0.23%$306,00036.6K
77NTLAINTELLIA THERAPEUTICS INCCOM0.22%$296,0003.7K
78UBSUBS GROUP AGSHS0.22%$292,00020.0K
79SCCOSOUTHERN COPPER CORPCOM0.19%$258,0003.8K
80VRAVERA BRADLEY INCCOM0.12%$164,00016.2K
81OVIDOVID THERAPEUTICS INCCOM0.12%$164,00040.9K
82BCRXBIOCRYST PHARMACEUTICALS INCCOM0.12%$156,00015.3K
83TILLYS INCCL A0.11%$149,00013.1K
84SRNESORRENTO THERAPEUTICS INCCOM NEW0.11%$149,00018.0K
85ORBCORBCOMM INCCOM0.10%$135,00017.7K
86CONSOLIDATED COMM HLDGS INCCOM0.09%$124,00017.2K
87EVCENTRAVISION COMMUNICATIONS CCL A0.09%$121,00029.9K
88IMMUNOGEN INCCOM0.09%$121,00014.9K
89FIVE STAR SENIOR LIVING INCCOM NEW0.08%$114,00018.6K
90TRUECAR INCCOM0.08%$107,00022.4K
91AFFIMED N VCOM0.08%$107,00013.4K
92CECOCECO ENVIRONMENTAL CORPCOM0.08%$105,00013.2K
93ARAYACCURAY INCCOM0.08%$104,00020.9K
94ATENA10 NETWORKS INCCOM0.08%$103,00010.7K
95WSRWHITESTONE REITCOM0.07%$100,00010.3K
96ACTGACACIA RESH CORPACACIA TCH COM0.07%$93,00014.0K
97LYTSLSI INDS INCCOM0.07%$92,00010.8K
98KDMNKADMON HLDGS INCCOM0.07%$92,00023.7K
99RLGTRADIANT LOGISTICS INCCOM0.07%$90,00012.9K
100VBI VACCINES INC CDACOM NEW0.07%$89,00028.6K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$362M156May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$388M145Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$408M148Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$272M146Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$260M148May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$269M137Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$290M142Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$274M138Aug 14, 202413F-HRchanges · EDGAR ↗
Q1 2024$280M131May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$276M126Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$216M132Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$219M134Aug 14, 202313F-HRchanges · EDGAR ↗
Q1 2023$123M108May 15, 202313F-HRchanges · EDGAR ↗
Q4 2022$168M105Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$175M113Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$166M110Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$157M86May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$126M69Feb 14, 202213F-HRchanges · EDGAR ↗
Q3 2021$151M127Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021$141M116Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$135M125May 17, 202113F-HRchanges · EDGAR ↗
Q4 2020$157M117Feb 16, 202113F-HRchanges · EDGAR ↗
Q3 2020$137M113Nov 16, 202013F-HRchanges · EDGAR ↗
Q2 2020$121M100Aug 14, 202013F-HRchanges · EDGAR ↗
Q1 2020$108M65May 15, 202013F-HRchanges · EDGAR ↗
Q4 2019$132M119Feb 14, 202013F-HRchanges · EDGAR ↗
Q3 2019$147M126Nov 14, 201913F-HRchanges · EDGAR ↗
Q2 2019$195M108Aug 14, 201913F-HRchanges · EDGAR ↗
Q1 2019$123M112May 15, 201913F-HRchanges · EDGAR ↗
Q4 2018$116M113Feb 14, 201913F-HRchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.