SEC 13F Intelligence

Managers / Q3 2024 · view latest →

Propel Bio Management, LLC

CIK 0001969764 · 11620 WILSHIRE BLVD.,, SUITE 350, LOS ANGELES, CA, 90025 · 908-507-9629

Reported Value
$172M
Q3 2024
Positions
21
Filings on Record
10
2019–present window
Filed
Nov 13, 2024
original filing

Summary

Propel Bio Management, LLC reported $172M in U.S.-listed holdings across 21 positions for Q3 2024.

The portfolio is heavily concentrated: APLT alone accounts for 32.4% of reported value.

Compared with Q2 2024, the fund opened 3 new positions and exited 6.

Portfolio Metrics

Turnover
+13.8%
vs prior filed quarter
Top-10 Concentration
+90.8%
share of reported value
Largest Position
+32.4%
Applied Therapeutics
New / Exited
3 / 6
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded, with multiple share classes and repeated sub-manager rows for the same issuer combined into one position — the same rule the holdings table uses by default. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’23: $121MQ4 ’23Q1 ’24: $172MQ2 ’24: $154MQ2 ’24Q3 ’24: $172MQ4 ’24: $101MQ4 ’24Q1 ’25: $86MQ2 ’25: $82MQ2 ’25Q3 ’25: $100MQ4 ’25: $117MQ4 ’25Q1 ’26: $159Mfilingsflow.com

Portfolio Composition

By security type
Common Stock: 85.4%Ltd Part: 13.7%Other: 0.7%ADR: 0.3%
  • Common Stock · 85.4% · $147M
  • Ltd Part · 13.7% · $24M
  • Other · 0.7% · $1M
  • ADR · 0.3% · $504,000

Quarter-over-Quarter Changes full breakdown →

vs Q2 2024 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
ZVRAZEVRA THERAPEUTICS INCNEW+179.9K179.9K+$1M$1M
CMPSCOMPASS PATHWAYS LTDNEW+80.0K80.0K+$504,000$504,000
MAAT PHARMA SACANEW+2.4K2.4K+$17,786$17,786
FULCFULCRUM THERAPEUTICS INCSOLD OUT750.0K0$5M$0
KYNKAYNE ANDERSON ENERGY INFSOLD OUT147.0K0$2M$0
TRVITREVI THERAPEUTICS INCSOLD OUT260.0K0$774,800$0
FIDELITY INV MMTRSY 1 680SOLD OUT317.0K0$317,014$0
CYBIN INCSOLD OUT850.0K0$230,350$0

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q3 2024

21 positions
#IssuerClass% PortfolioValueShares
1APLTAPPLIED THERAPEUTICS INChistory →COMM32.38%$56M6.57M
2PAGPPLAINS GP HOLDINGS LP-CLhistory →COMM13.65%$24M1.27M
3PHATPHATHOM PHARMACEUTICALS Ihistory →COMM9.12%$16M869.9K
4ACHVACHIEVE LIFE SCIENCES INChistory →COMM6.74%$12M2.45M
5TCRXTSCAN THERAPEUTICS INChistory →COMM6.03%$10M2.09M
6AKROAKERO THERAPEUTICS INChistory →COMM5.72%$10M343.7K
7MDGLMADRIGAL PHARMACEUTICALShistory →COMM5.30%$9M43.0K
8AVIDITY BIOSCIENCES INCCOMM4.76%$8M178.5K
9ARDXARDELYX INChistory →COMM4.28%$7M1.07M
10TSATTELESAT CORPhistory →COMM2.79%$5M365.8K
11ABEOABEONA THERAPEUTICS INChistory →COMM2.29%$4M624.0K
12KYMRKYMERA THERAPEUTICS INChistory →COMM1.55%$3M56.4K
13SNDXSYNDAX PHARMACEUTICALS INhistory →COMM1.49%$3M133.3K
14KURAKURA ONCOLOGY INChistory →COMM1.47%$3M130.0K
15ZVRAZEVRA THERAPEUTICS INCCOMM0.72%$1M179.9K
16EIGER BIOPHARMACEUTICALSCOMM0.72%$1M146.4K
17ATHIRA PHARMA INCCOMM0.39%$665,7851.49M
18CMPSCOMPASS PATHWAYS LTDCOMM0.29%$504,00080.0K
19VERRICA PHARMACEUTICALS ICOMM0.29%$500,159344.9K
20MAAT PHARMA SACACOMM0.01%$17,7862.4K
21CHINOOK THERAPEUTICSCOMM0.01%$9,75079.4K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$159M38May 14, 202613F-HRchanges · EDGAR ↗
Q4 2025$117M20Feb 11, 202613F-HRchanges · EDGAR ↗
Q3 2025$100M16Nov 12, 202513F-HRchanges · EDGAR ↗
Q2 2025$82M16Aug 13, 202513F-HRchanges · EDGAR ↗
Q1 2025$86M18May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$101M21Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$172M21Nov 13, 202413F-HRchanges · EDGAR ↗
Q2 2024$154M25Aug 12, 202413F-HRchanges · EDGAR ↗
Q1 2024$172M29May 13, 202413F-HRchanges · EDGAR ↗
Q4 2023$121M34Feb 14, 202413F-HRchanges · EDGAR ↗

Other Included Managers

This filing reports holdings on behalf of 1 additional manager.

  • Simplify Asset Management Inc.028-20937

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.