SEC 13F Intelligence

Managers / Q4 2023 · view latest →

Propel Bio Management, LLC

CIK 0001969764 · 11620 WILSHIRE BLVD.,, SUITE 350, LOS ANGELES, CA, 90025 · 908-507-9629

Reported Value
$121M
Q4 2023
Positions
34
Filings on Record
10
2019–present window
Filed
Feb 14, 2024
original filing

Summary

Propel Bio Management, LLC reported $121M in U.S.-listed holdings across 34 positions for Q4 2023.

Its largest position, PAGP, represents 18.1% of the portfolio.

Portfolio Metrics

Top-10 Concentration
+71.6%
share of reported value
Largest Position
+18.1%
Plains GP Holdings LP Cl

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded, with multiple share classes and repeated sub-manager rows for the same issuer combined into one position — the same rule the holdings table uses by default. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’23: $121MQ4 ’23Q1 ’24: $172MQ2 ’24: $154MQ2 ’24Q3 ’24: $172MQ4 ’24: $101MQ4 ’24Q1 ’25: $86MQ2 ’25: $82MQ2 ’25Q3 ’25: $100MQ4 ’25: $117MQ4 ’25Q1 ’26: $159Mfilingsflow.com

Portfolio Composition

By security type
Common Stock: 63.1%Ltd Part: 18.1%ETP: 10.0%Other: 7.7%Closed-End Fund: 1.1%
  • Common Stock · 63.1% · $76M
  • Ltd Part · 18.1% · $22M
  • ETP · 10.0% · $12M
  • Other · 7.7% · $9M
  • Closed-End Fund · 1.1% · $1M

Quarter-over-Quarter Changes full breakdown →

IssuerMoveShare ΔShares nowValue ΔValue now
PAGPPLAINS GP HOLDINGS LP-CLNEW+1.37M1.37M+$22M$22M
APLTAPPLIED THERAPEUTICS INCNEW+5.37M5.37M+$18M$18M
TCRXTSCAN THERAPEUTICS INCNEW+2.09M2.09M+$12M$12M
MDGLMADRIGAL PHARMACEUTICALS INCNEW+30.0K30.0K+$7M$7M
CRNXCRINETICS PHARMACEUTICALS INNEW+165.0K165.0K+$6M$6M
FULCFULCRUM THERAPEUTICS INCNEW+750.0K750.0K+$5M$5M
FIDELITY INV MMTRSY 1 680NEW+4.77M4.77M+$5M$5M
PHATPHATHOM PHARMACEUTICALS INCNEW+443.0K443.0K+$4M$4M

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q4 2023

34 positions
#IssuerClass% PortfolioValueShares
1PAGPPLAINS GP HOLDINGS LP-CLhistory →COMM18.15%$22M1.37M
2APLTAPPLIED THERAPEUTICS INChistory →COMM14.93%$18M5.37M
3TCRXTSCAN THERAPEUTICS INChistory →COMM10.09%$12M2.09M
4MDGLMADRIGAL PHARMACEUTICALS INChistory →COMM5.76%$7M30.0K
5CRNXCRINETICS PHARMACEUTICALS INhistory →COMM4.87%$6M165.0K
6FULCFULCRUM THERAPEUTICS INChistory →COMM4.20%$5M750.0K
7FIDELITY INV MMTRSY 1 680COMM3.96%$5M4.77M
8PHATPHATHOM PHARMACEUTICALS INChistory →COMM3.35%$4M443.0K
9DAY ONE BIOPHARMACEUTICALS ICOMM3.28%$4M270.7K
10ARDXARDELYX INChistory →COMM3.05%$4M594.2K
11ATHIRA PHARMA INCCOMM3.01%$4M1.49M
12TSATTELESAT CORPhistory →COMM2.51%$3M290.8K
13HIGHSIMPLIFY ENHANCED INCOMEhistory →COMM2.45%$3M120.2K
14AKROAKERO THERAPEUTICS INChistory →COMM1.94%$2M100.1K
15BSVVANGUARD SHORT-TERM BONDhistory →COMM1.77%$2M27.7K
16ISHARES IBONDS DEC 2024 TCOMM1.76%$2M85.4K
17MBBISHARES MBS ETFhistory →COMM1.75%$2M22.4K
18MIRMMIRUM PHARMACEUTICALS INChistory →COMM1.71%$2M70.0K
19MARINUS PHARMACEUTICALS INCCOMM1.62%$2M180.1K
20KURAKURA ONCOLOGY INChistory →COMM1.55%$2M130.0K
21AVIDITY BIOSCIENCES INCCOMM1.34%$2M178.5K
22KYMRKYMERA THERAPEUTICS INChistory →COMM1.19%$1M56.4K
23SPSBSPDR PORT SHRT TRM CORP Bhistory →COMM1.13%$1M45.7K
24KYNKAYNE ANDERSON ENERGY INFhistory →COMM1.07%$1M147.0K
25EIGER BIOPHARMACEUTICALS INCCOMM0.82%$985,8764.39M
26SUTRO BIOPHARMA INCCOMM0.69%$836,550195.0K
27SLQDISHARES 0-5 YR INV GRD COCOMM0.50%$597,68212.1K
28ISHARES IBOXX INVESTMENTCOMM0.41%$493,1014.5K
29X4 PHARMACEUTICALS INCCOMM0.37%$448,598535.0K
30CYBIN INCCOMM0.29%$348,500850.0K
31FLRNSPDR BLOOMBERG INVESTMENTCOMM0.24%$283,4789.3K
32HRTXHERON THERAPEUTICS INCCOMM0.15%$177,132104.2K
33AGIOAGIOS PHARMACEUTICALS INCCOMM0.11%$128,9885.8K
34CHINOOK THERAPEUTICS INC CVRCOMM0.00%$079.4K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$159M38May 14, 202613F-HRchanges · EDGAR ↗
Q4 2025$117M20Feb 11, 202613F-HRchanges · EDGAR ↗
Q3 2025$100M16Nov 12, 202513F-HRchanges · EDGAR ↗
Q2 2025$82M16Aug 13, 202513F-HRchanges · EDGAR ↗
Q1 2025$86M18May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$101M21Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$172M21Nov 13, 202413F-HRchanges · EDGAR ↗
Q2 2024$154M25Aug 12, 202413F-HRchanges · EDGAR ↗
Q1 2024$172M29May 13, 202413F-HRchanges · EDGAR ↗
Q4 2023$121M34Feb 14, 202413F-HRchanges · EDGAR ↗

Other Included Managers

This filing reports holdings on behalf of 1 additional manager.

  • Simplify Asset Management Inc.028-20937

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.