SEC 13F Intelligence

Managers / Q1 2024 · view latest →

Propel Bio Management, LLC

CIK 0001969764 · 11620 WILSHIRE BLVD.,, SUITE 350, LOS ANGELES, CA, 90025 · 908-507-9629

Reported Value
$172M
Q1 2024
Positions
29
Filings on Record
10
2019–present window
Filed
May 13, 2024
original filing

Summary

Propel Bio Management, LLC reported $172M in U.S.-listed holdings across 29 positions for Q1 2024.

The portfolio is heavily concentrated: APLT alone accounts for 24.2% of reported value.

Compared with Q4 2023, the fund opened 4 new positions and exited 10.

Portfolio Metrics

Turnover
+28.3%
vs prior filed quarter
Top-10 Concentration
+81.2%
share of reported value
Largest Position
+24.2%
Applied Therapeutics
New / Exited
4 / 10
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’23: $121MQ4 ’23Q1 ’24: $172MQ2 ’24: $154MQ2 ’24Q3 ’24: $172MQ4 ’24: $101MQ4 ’24Q1 ’25: $86MQ2 ’25: $82MQ2 ’25Q3 ’25: $100MQ4 ’25: $117MQ4 ’25Q1 ’26: $159Mfilingsflow.com

Portfolio Composition

By security type
Common Stock: 78.2%ETP: 17.8%Other: 3.2%Closed-End Fund: 0.9%
  • Common Stock · 78.2% · $134M
  • ETP · 17.8% · $31M
  • Other · 3.2% · $5M
  • Closed-End Fund · 0.9% · $1M

Quarter-over-Quarter Changes full breakdown →

vs Q4 2023 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
SP4PACHIEVE LIFE SCIENCES INCNEW+2.45M2.45M+$11M$11M
SNDXSYNDAX PHARMACEUTICALS INCNEW+83.3K83.3K+$2M$2M
TRVITREVI THERAPEUTICS INCNEW+260.0K260.0K+$897,000$897,000
72CEIGER BIOPHARMACEUTICALS INCNEW+146.4K146.4K+$731,905$731,905
SIMPLIFY ENHANCED INCOMEADDED+1.37M1.49M+$25M$28M
AKROAKERO THERAPEUTICS INCADDED+227.7K327.8K+$6M$8M
PAGPEURPLAINS GP HOLDINGS LP-CLSOLD OUT1.37M0$22M$0
CRNXCRINETICS PHARMACEUTICALS INSOLD OUT165.0K0$6M$0

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q1 2024

29 positions
#IssuerClass% PortfolioValueShares
1APLTAPPLIED THERAPEUTICS INChistory →COMM24.19%$42M6.11M
2PLAINS GP HOLDINGS LP-CLCOMM14.58%$25M1.37M
3TCRXTSCAN THERAPEUTICS INChistory →COMM9.65%$17M2.09M
4MDGLMADRIGAL PHARMACEUTICALS INChistory →COMM6.69%$11M43.0K
5SP4PACHIEVE LIFE SCIENCES INChistory →COMM6.49%$11M2.45M
6PHATPHATHOM PHARMACEUTICALS INChistory →COMM5.38%$9M869.9K
7AKROAKERO THERAPEUTICS INChistory →COMM4.82%$8M327.8K
8FULCFULCRUM THERAPEUTICS INChistory →COMM4.12%$7M750.0K
9RNAGBPAVIDITY BIOSCIENCES INChistory →COMM2.65%$5M178.5K
10DAWNGBXDAY ONE BIOPHARMACEUTICALS Ihistory →COMM2.60%$4M270.7K
11ARDXARDELYX INChistory →COMM2.52%$4M594.2K
12ATHIRA PHARMA INCCOMM2.38%$4M1.49M
13SIMPLIFY ENHANCED INCOMECOMM1.71%$3M120.2K
14KURAKURA ONCOLOGY INChistory →COMM1.61%$3M130.0K
15TSATTELESAT CORPhistory →COMM1.46%$3M290.8K
16KYMRKYMERA THERAPEUTICS INChistory →COMM1.32%$2M56.4K
17ISHARES MBS ETFCOMM1.20%$2M22.4K
18SNDXSYNDAX PHARMACEUTICALS INChistory →COMM1.15%$2M83.3K
19MIRMMIRUM PHARMACEUTICALS INChistory →COMM1.02%$2M70.0K
20MARINUS PHARMACEUTICALS INCCOMM0.95%$2M180.1K
21KYNEURKAYNE ANDERSON ENERGY INFCOMM0.86%$1M147.0K
22SUTRO BIOPHARMA INCCOMM0.64%$1M195.0K
23TRVITREVI THERAPEUTICS INCCOMM0.52%$897,000260.0K
24ASNSUSDX4 PHARMACEUTICALS INCCOMM0.43%$743,650535.0K
2572CEIGER BIOPHARMACEUTICALS INCCOMM0.43%$731,905146.4K
26ISHARES IBOXX INVESTMENTCOMM0.28%$485,3484.5K
27CYBNEURCYBIN INCCOMM0.20%$351,475850.0K
28FIDELITY INV MMTRSY 1 680COMM0.12%$211,541211.5K
29CHINOOK THERAPEUTICS INC CVRCOMM0.02%$30,94979.4K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$159M38May 14, 202613F-HRchanges · EDGAR ↗
Q4 2025$117M20Feb 11, 202613F-HRchanges · EDGAR ↗
Q3 2025$100M16Nov 12, 202513F-HRchanges · EDGAR ↗
Q2 2025$82M16Aug 13, 202513F-HRchanges · EDGAR ↗
Q1 2025$86M18May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$101M21Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$172M21Nov 13, 202413F-HRchanges · EDGAR ↗
Q2 2024$154M25Aug 12, 202413F-HRchanges · EDGAR ↗
Q1 2024$172M29May 13, 202413F-HRchanges · EDGAR ↗
Q4 2023$121M34Feb 14, 202413F-HRchanges · EDGAR ↗

Other Included Managers

This filing reports holdings on behalf of 1 additional manager.

  • Simplify Asset Management Inc.028-20937

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.