SEC 13F Intelligence

Managers / Q4 2021 · view latest →

SECTORAL ASSET MANAGEMENT INC

CIK 0001274413 · 1010 SHERBROOKE ST., WEST, SUITE 1610, MONTREAL, A8, H3A 2R7 · 514 849 8777

Reported Value
$664M
Q4 2021
Positions
108
Filings on Record
30
2019–present window
Filed
Feb 11, 2022
original filing

Summary

Sectoral Asset Management Inc reported $664M in U.S.-listed holdings across 108 positions for Q4 2021.

Its largest position, ARNAEUR, represents 3.2% of the portfolio.

Compared with Q3 2021, the fund opened 16 new positions and exited 35.

Portfolio Metrics

Turnover
+12.6%
vs prior filed quarter
Top-10 Concentration
+25.3%
share of reported value
Largest Position
+3.2%
Arena Pharmaceuticals
New / Exited
16 / 35
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’18: $736MQ4 ’18Q1 ’19: $831MQ2 ’19: $836MQ3 ’19: $580MQ4 ’19: $670MQ4 ’19Q1 ’20: $521MQ2 ’20: $1.1BQ3 ’20: $1.2BQ4 ’20: $1.4BQ4 ’20Q1 ’21: $1.3BQ2 ’21: $1.2BQ3 ’21: $1.2BQ4 ’21: $664MQ4 ’21Q1 ’22: $563MQ2 ’22: $496MQ3 ’22: $508MQ4 ’22: $517MQ4 ’22Q1 ’23: $520MQ2 ’23: $600MQ3 ’23: $514MQ4 ’23: $232MQ4 ’23Q1 ’24: $254MQ2 ’24: $246MQ3 ’24: $169MQ4 ’24: $150MQ4 ’24Q1 ’25: $128MQ2 ’25: $151MQ3 ’25: $162MQ4 ’25: $125MQ4 ’25Q1 ’26: $121Mfilingsflow.com

Portfolio Composition

By security type
Common Stock: 83.4%Other: 15.2%ADR: 1.4%
  • Common Stock · 83.4% · $554M
  • Other · 15.2% · $101M
  • ADR · 1.4% · $9M

Quarter-over-Quarter Changes full breakdown →

vs Q3 2021 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
PRVAPRIVIA HEALTH GROUP INCNEW+401.6K401.6K+$10M$10M
CERTCERTARA INCNEW+350.4K350.4K+$10M$10M
DHDEFINITIVE HEALTHCARE CORPNEW+285.3K285.3K+$8M$8M
2655787DBLUEPRINT MEDICINES CORPNEW+65.8K65.8K+$7M$7M
ARWRARROWHEAD PHARMACEUTICALS INNEW+104.8K104.8K+$7M$7M
EXAIEUREXSCIENTIA PLCNEW+301.4K301.4K+$6M$6M
MRVIMARAVAI LIFESCIENCES HLDGS INEW+110.0K110.0K+$5M$5M
BTTXBETTER THERAPEUTICS INCNEW+973.8K973.8K+$5M$5M

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q4 2021

50 positions
Export to Excel
#IssuerClass% PortfolioValue ↓Shares
1ARNAEURARENA PHARMACEUTICALS INChistory →COM NEW3.22%$21M230.0K
2EFFECTOR THERAPEUTICS INCCOM2.97%$20M2.38M
3ORTHO CLINICAL DIAGNOSTICS HORD SHS2.80%$19M870.3K
48INSYNEOS HEALTH INChistory →CL A2.54%$17M164.3K
5ATRCATRICURE INChistory →COM2.42%$16M231.2K
6RCMEURR1 RCM INChistory →COM2.33%$15M607.5K
7EVHEVOLENT HEALTH INChistory →CL A2.30%$15M552.0K
8UNHUNITEDHEALTH GROUP INChistory →COM2.29%$15M30.3K
9INARI MED INCCOM2.25%$15M163.6K
10ARVNARVINAS INChistory →COM2.20%$15M178.2K
11IM8NINSMED INChistory →COM PAR $.012.17%$14M528.3K
12AM6AMICUS THERAPEUTICS INChistory →COM2.16%$14M1.24M
13JNJJOHNSON & JOHNSONhistory →COM1.92%$13M74.5K
14PFEPFIZER INChistory →COM1.85%$12M208.4K
15INSPINSPIRE MED SYS INChistory →COM1.79%$12M51.6K
16THCTENET HEALTHCARE CORPhistory →COM NEW1.76%$12M143.0K
17RCUSARCUS BIOSCIENCES INChistory →COM1.73%$11M283.2K
18TMOTHERMO FISHER SCIENTIFIC INChistory →COM1.72%$11M17.1K
19FATEFATE THERAPEUTICS INChistory →COM1.70%$11M193.2K
20MRTXEURMIRATI THERAPEUTICS INChistory →COM1.67%$11M75.8K
21TURNING POINT THERAPEUTICS ICOM1.58%$10M219.8K
22PTCTPTC THERAPEUTICS INChistory →COM1.57%$10M262.3K
23AGILITI INCCOM1.57%$10M449.7K
24PRVAPRIVIA HEALTH GROUP INChistory →COM1.56%$10M401.6K
25ALHCALIGNMENT HEALTHCARE INChistory →COM1.54%$10M729.5K
26CERTCERTARA INChistory →COM1.50%$10M350.4K
27ABTABBOTT LABShistory →COM1.45%$10M68.5K
28HCATHEALTH CATALYST INChistory →COM1.44%$10M241.7K
29ABBVABBVIE INChistory →COM1.40%$9M68.8K
30SILKUSDSILK RD MED INChistory →COM1.34%$9M209.0K
31NTLAINTELLIA THERAPEUTICS INChistory →COM1.27%$8M71.6K
32DNLIDENALI THERAPEUTICS INChistory →COM1.27%$8M189.6K
33RCKTROCKET PHARMACEUTICALS INChistory →COM1.26%$8M383.0K
34LLYLILLY ELI & COhistory →COM1.22%$8M29.5K
35DHDEFINITIVE HEALTHCARE CORPhistory →CLASS A COM1.17%$8M285.3K
36TGTXTG THERAPEUTICS INChistory →COM1.14%$8M399.9K
37EX9EXELIXIS INChistory →COM1.13%$7M409.9K
382655787DBLUEPRINT MEDICINES CORPhistory →COM1.06%$7M65.8K
39ARWRARROWHEAD PHARMACEUTICALS INhistory →COM1.05%$7M104.8K
40NVV1NOVAVAX INCCOM NEW0.95%$6M44.3K
41INVITAE CORPCOM0.94%$6M410.8K
42SWAVUSDSHOCKWAVE MED INCCOM0.94%$6M35.0K
43EXAIEUREXSCIENTIA PLCADS0.90%$6M301.4K
44BLUBELLUS HEALTH INC NEWCOM NEW0.87%$6M722.0K
45SGENUSDSEAGEN INCCOM0.86%$6M36.9K
46STAASTAAR SURGICAL COCOM PAR $0.010.86%$6M62.5K
47BSXBOSTON SCIENTIFIC CORPCOM0.83%$6M130.2K
48DHRDANAHER CORPORATIONCOM0.83%$6M16.8K
49AFWALIGN TECHNOLOGY INCCOM0.82%$5M8.3K
50BERKELEY LTS INCCOM0.80%$5M291.8K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$121M77May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$125M74Feb 9, 202613F-HRchanges · EDGAR ↗
Q3 2025$162M82Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$151M94Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$128M84May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$150M86Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$169M90Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$246M97Aug 13, 202413F-HRchanges · EDGAR ↗
Q1 2024$254M92May 14, 202413F-HRchanges · EDGAR ↗
Q4 2023$232M104Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$514M123Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$600M121Aug 11, 202313F-HRchanges · EDGAR ↗
Q1 2023$520M118May 12, 202313F-HRchanges · EDGAR ↗
Q4 2022$517M120Feb 10, 202313F-HRchanges · EDGAR ↗
Q3 2022$508M109Nov 10, 202213F-HRchanges · EDGAR ↗
Q2 2022$496M112Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$563M106May 10, 202213F-HRchanges · EDGAR ↗
Q4 2021$664M108Feb 11, 202213F-HRchanges · EDGAR ↗
Q3 2021$1.2B127Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021$1.2B127Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$1.3B113May 14, 202113F-HRchanges · EDGAR ↗
Q4 2020$1.4B97Feb 12, 202113F-HRchanges · EDGAR ↗
Q3 2020$1.2B88Nov 13, 202013F-HRchanges · EDGAR ↗
Q2 2020$1.1B191Aug 13, 202013F-HRchanges · EDGAR ↗
Q1 2020$521M65May 13, 202013F-HRchanges · EDGAR ↗
Q4 2019$670M65Feb 12, 202013F-HRchanges · EDGAR ↗
Q3 2019$580M63Nov 14, 201913F-HRchanges · EDGAR ↗
Q2 2019$836M92Aug 14, 201913F-HRchanges · EDGAR ↗
Q1 2019$831M106May 14, 201913F-HRchanges · EDGAR ↗
Q4 2018$736M104Feb 12, 201913F-HRchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.