SEC 13F Intelligence

Managers / Q1 2026

SECTORAL ASSET MANAGEMENT INC

CIK 0001274413 · 1010 SHERBROOKE ST., WEST, SUITE 1610, MONTREAL, A8, H3A 2R7 · 514 849 8777

Reported Value
$121M
Q1 2026
Positions
77
Filings on Record
30
2019–present window
Filed
May 15, 2026
original filing

Summary

Sectoral Asset Management Inc reported $121M in U.S.-listed holdings across 77 positions for Q1 2026.

Its largest position, EVMN, represents 11.2% of the portfolio.

Compared with Q4 2025, the fund opened 10 new positions and exited 7.

Portfolio Metrics

Turnover
+13.2%
vs prior filed quarter
Top-10 Concentration
+48.1%
share of reported value
Largest Position
+11.2%
Evommune
New / Exited
10 / 7
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’18: $736MQ4 ’18Q1 ’19: $831MQ2 ’19: $836MQ3 ’19: $580MQ4 ’19: $670MQ4 ’19Q1 ’20: $521MQ2 ’20: $1.1BQ3 ’20: $1.2BQ4 ’20: $1.4BQ4 ’20Q1 ’21: $1.3BQ2 ’21: $1.2BQ3 ’21: $1.2BQ4 ’21: $664MQ4 ’21Q1 ’22: $563MQ2 ’22: $496MQ3 ’22: $508MQ4 ’22: $517MQ4 ’22Q1 ’23: $520MQ2 ’23: $600MQ3 ’23: $514MQ4 ’23: $232MQ4 ’23Q1 ’24: $254MQ2 ’24: $246MQ3 ’24: $169MQ4 ’24: $150MQ4 ’24Q1 ’25: $128MQ2 ’25: $151MQ3 ’25: $162MQ4 ’25: $125MQ4 ’25Q1 ’26: $121Mfilingsflow.com

Portfolio Composition

By security type
Common Stock: 90.4%ADR: 5.7%Other: 3.9%
  • Common Stock · 90.4% · $109M
  • ADR · 5.7% · $7M
  • Other · 3.9% · $5M

Quarter-over-Quarter Changes full breakdown →

vs Q4 2025 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
IQVIQVIA HOLDINGS INCNEW+8.3K8.3K+$1M$1M
BMYBRISTOL MYERS SQUIBBNEW+21.1K21.1K+$1M$1M
MEDTRONIC PLCNEW+11.1K11.1K+$961,815$961,815
ARDXARDELYX INCNEW+122.4K122.4K+$781,060$781,060
AGMBAGOMAB THERAPEUTICSNEW+43.5K43.5K+$477,295$477,295
ABVXABIVAX SANEW+2.3K2.3K+$297,861$297,861
MEDPMEDPACE HOLDINGSNEW+430430+$228,090$228,090
GHGUARDANT HEALTH INCNEW+2.0K2.0K+$205,523$205,523

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q1 2026

50 positions
Export to Excel
#IssuerClass% PortfolioValue ↓Shares
1EVMNEVOMMUNE INChistory →COM SHS11.22%$14M589.0K
2CTNMCONTINEUM THERAPEUTICShistory →CL A7.87%$10M727.6K
3SISHOULDER INNOVATIONShistory →COMMON STOCK5.18%$6M430.4K
4LLYELI LILLY & COhistory →COM4.84%$6M6.4K
5JNJJOHNSON & JOHNSONhistory →COM3.69%$4M18.2K
6GILDGILEAD SCIENCES INChistory →COM3.42%$4M27.5K
7UNHUNITEDHEALTH GRP INChistory →COM3.35%$4M15.0K
8AMGNAMGEN INChistory →COM2.91%$4M9.2K
9VRTXVERTEX PHARMAhistory →COM2.86%$3M7.0K
10IM8NINSMED INChistory →COM PAR $.012.80%$3M19.7K
11ARGXARGENX SEhistory →SP ADR2.27%$3M3.6K
12ABBVABBVIE INChistory →COM2.20%$3M12.2K
13ABTABBOTT LABShistory →COM2.18%$3M25.6K
14MRKMERCK & CO INChistory →COM2.14%$3M21.5K
15REGNREGENERON PHARMCTCLShistory →COM2.06%$2M2.9K
16ISRGINTUITIVE SURGIC INChistory →COM NEW2.00%$2M5.3K
17BSXBOSTON SCIENTIFIChistory →COM1.81%$2M34.8K
18BNTXBIONTECH SEhistory →SP ADR1.69%$2M22.2K
19SYKSTRYKER CORPhistory →COM1.60%$2M5.9K
20DHRDANAHER CORPhistory →COM1.51%$2M9.6K
21TMOTHERMO FISHER SCIENTIFIChistory →COM1.43%$2M3.5K
22DC4DEXCOM INChistory →COM1.21%$1M23.2K
23IQVIQVIA HOLDINGS INChistory →COM1.17%$1M8.3K
24SMMTSUMMIT THERAPEUTICShistory →COM1.16%$1M69.6K
25EWEDWARDS LIFESCIENCEShistory →COM1.15%$1M17.3K
26BMYBRISTOL MYERS SQUIBBhistory →COM1.06%$1M21.1K
27UTHUNITED THERAPEUTICSCOM0.95%$1M1.7K
28VERAVERA THERAPEUTICSCL A0.90%$1M25.6K
29RCUSARCUS BIOSCIENCESCOM0.86%$1M45.1K
30ROIVANT SCIENCES LTDSHS0.84%$1M32.5K
31MEDTRONIC PLCSHS0.80%$961,81511.1K
32TRVITREVI THERAPEUTICSCOM0.78%$939,49974.4K
33COGTCOGENT BIOSCIENCESCOM0.75%$902,39822.1K
34MLYSMINERALYS THERAPEUTICSCOM0.74%$895,13531.6K
35ALNYALNYLAM PHARMACUETCLCOM0.72%$864,2322.3K
36TARSTARSUS PHARMACEUTICALSCOM0.71%$852,46311.3K
37RAPPRAPPORT THERAPEUTICSCOM0.69%$835,00525.4K
38NKTRNEKTAR THERAPEUTICSCOM NEW0.68%$820,66210.9K
39SNDXSYNDAX PHARMACEUTICSCOM0.65%$787,46631.7K
40ARDXARDELYX INCCOM0.65%$781,060122.4K
41PFEPFIZER INCCOM0.64%$772,20027.5K
42BOLDBOUNDLESS BIOCOM0.62%$746,431678.6K
43ASCENDIS PHARMA A SSP ADR0.60%$728,2762.8K
44AVBPARRIVENT BIOPHARMACOM0.60%$720,43030.0K
45GPCRSTRUCTURE THERAPEUTICSSP ADR0.59%$710,80514.1K
46IMMATICS NVSHS0.57%$692,68766.8K
47BBIOBRIDGEBIO PHARMACOM0.57%$687,2768.1K
48SPRYARS PHARMACEUTICALSCOM0.56%$676,67279.2K
49ONCBEONE MEDICINES LTDSP ADR0.52%$631,0611.9K
50TECXTECTONIC THERAPEUTICCOM0.52%$628,21519.1K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$121M77May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$125M74Feb 9, 202613F-HRchanges · EDGAR ↗
Q3 2025$162M82Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$151M94Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$128M84May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$150M86Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$169M90Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$246M97Aug 13, 202413F-HRchanges · EDGAR ↗
Q1 2024$254M92May 14, 202413F-HRchanges · EDGAR ↗
Q4 2023$232M104Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$514M123Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$600M121Aug 11, 202313F-HRchanges · EDGAR ↗
Q1 2023$520M118May 12, 202313F-HRchanges · EDGAR ↗
Q4 2022$517M120Feb 10, 202313F-HRchanges · EDGAR ↗
Q3 2022$508M109Nov 10, 202213F-HRchanges · EDGAR ↗
Q2 2022$496M112Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$563M106May 10, 202213F-HRchanges · EDGAR ↗
Q4 2021$664M108Feb 11, 202213F-HRchanges · EDGAR ↗
Q3 2021$1.2B127Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021$1.2B127Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$1.3B113May 14, 202113F-HRchanges · EDGAR ↗
Q4 2020$1.4B97Feb 12, 202113F-HRchanges · EDGAR ↗
Q3 2020$1.2B88Nov 13, 202013F-HRchanges · EDGAR ↗
Q2 2020$1.1B191Aug 13, 202013F-HRchanges · EDGAR ↗
Q1 2020$521M65May 13, 202013F-HRchanges · EDGAR ↗
Q4 2019$670M65Feb 12, 202013F-HRchanges · EDGAR ↗
Q3 2019$580M63Nov 14, 201913F-HRchanges · EDGAR ↗
Q2 2019$836M92Aug 14, 201913F-HRchanges · EDGAR ↗
Q1 2019$831M106May 14, 201913F-HRchanges · EDGAR ↗
Q4 2018$736M104Feb 12, 201913F-HRchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.