SEC 13F Intelligence

Managers / Q2 2025 · view latest →

Paradigm Biocapital Advisors LP

CIK 0001855655 · 520 FIFTH AVENUE, 23RD FLOOR, NEW YORK, NY, 10036 · 646-970-2123

Reported Value
$2.3B
Q2 2025
Positions
28
Filings on Record
18
2019–present window
Filed
Aug 14, 2025
original filing

Summary

Paradigm Biocapital Advisors Lp reported $2.3B in U.S.-listed holdings across 28 positions for Q2 2025.

Its largest position, NUVL, represents 17.2% of the portfolio.

Compared with Q1 2025, the fund opened 6 new positions and exited 5.

Reported Value by Quarter

13F Reported Value
Q4 ’21: $350MQ4 ’21Q1 ’22: $378MQ2 ’22: $502MQ3 ’22: $750MQ3 ’22Q4 ’22: $851.9BQ1 ’23: $1.1BQ2 ’23: $1.3BQ2 ’23Q3 ’23: $1.5BQ4 ’23: $2.1BQ1 ’24: $2.8BQ1 ’24Q2 ’24: $2.6BQ3 ’24: $3.0BQ4 ’24: $2.9BQ4 ’24Q1 ’25: $2.2BQ2 ’25: $2.3BQ3 ’25: $3.5BQ3 ’25Q4 ’25: $3.9BQ1 ’26: $4.9Bfilingsflow.com

Portfolio Composition

By security type
Common Stock: 83.1%Other: 13.3%ADR: 3.6%
  • Common Stock · 83.1% · $1.9B
  • Other · 13.3% · $311M
  • ADR · 3.6% · $84M

Quarter-over-Quarter Changes full breakdown →

Holdings — Q2 2025

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Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$4.9B35May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$3.9B30Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$3.5B36Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$2.3B28Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$2.2B28May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$2.9B28Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$3.0B33Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$2.6B35Aug 14, 202413F-HRchanges · EDGAR ↗
Q1 2024$2.8B34May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$2.1B30Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$1.5B31Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$1.3B30Aug 14, 202313F-HRchanges · EDGAR ↗
Q1 2023$1.1B25May 15, 202313F-HRchanges · EDGAR ↗
Q4 2022$851.9B23Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$750M28Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$502M23Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$378M25May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$350M24Feb 14, 202213F-HRchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.