Managers / Q1 2026
Paradigm Biocapital Advisors LP
CIK 0001855655 · 520 FIFTH AVENUE, 23RD FLOOR, NEW YORK, NY, 10036 · 646-970-2123
Reported Value
$4.9B
Q1 2026
Positions
35
Filings on Record
18
2019–present window
Filed
May 15, 2026
original filing
Summary
Paradigm Biocapital Advisors Lp reported $4.9B in U.S.-listed holdings across 35 positions for Q1 2026.
Its largest position, ACLXGBX, represents 13.5% of the portfolio.
Compared with Q4 2025, the fund opened 10 new positions and exited 5.
Reported Value by Quarter
13F Reported Value
Portfolio Composition
By security type
- Common Stock · 85.7% · $4.2B
- ADR · 13.6% · $668M
- Other · 0.6% · $31M
Quarter-over-Quarter Changes full breakdown →
Holdings — Q1 2026
Filing History
| Quarter | Reported Value | Positions | Filed | Type | Links |
|---|---|---|---|---|---|
| Q1 2026 | $4.9B | 35 | May 15, 2026 | 13F-HR | changes · EDGAR ↗ |
| Q4 2025 | $3.9B | 30 | Feb 17, 2026 | 13F-HR | changes · EDGAR ↗ |
| Q3 2025 | $3.5B | 36 | Nov 14, 2025 | 13F-HR | changes · EDGAR ↗ |
| Q2 2025 | $2.3B | 28 | Aug 14, 2025 | 13F-HR | changes · EDGAR ↗ |
| Q1 2025 | $2.2B | 28 | May 15, 2025 | 13F-HR | changes · EDGAR ↗ |
| Q4 2024 | $2.9B | 28 | Feb 14, 2025 | 13F-HR | changes · EDGAR ↗ |
| Q3 2024 | $3.0B | 33 | Nov 14, 2024 | 13F-HR | changes · EDGAR ↗ |
| Q2 2024 | $2.6B | 35 | Aug 14, 2024 | 13F-HR | changes · EDGAR ↗ |
| Q1 2024 | $2.8B | 34 | May 15, 2024 | 13F-HR | changes · EDGAR ↗ |
| Q4 2023 | $2.1B | 30 | Feb 14, 2024 | 13F-HR | changes · EDGAR ↗ |
| Q3 2023 | $1.5B | 31 | Nov 14, 2023 | 13F-HR | changes · EDGAR ↗ |
| Q2 2023 | $1.3B | 30 | Aug 14, 2023 | 13F-HR | changes · EDGAR ↗ |
| Q1 2023 | $1.1B | 25 | May 15, 2023 | 13F-HR | changes · EDGAR ↗ |
| Q4 2022 | $851.9B | 23 | Feb 14, 2023 | 13F-HR | changes · EDGAR ↗ |
| Q3 2022 | $750M | 28 | Nov 14, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q2 2022 | $502M | 23 | Aug 15, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q1 2022 | $378M | 25 | May 16, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q4 2021 | $350M | 24 | Feb 14, 2022 | 13F-HR | changes · EDGAR ↗ |
13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.