SEC 13F Intelligence

Managers / Q2 2025 · view latest →

venBio Partners LLC

CIK 0001776382 · 1700 OWENS STREET, SUITE 595, SAN FRANCISCO, CA, 94158 · 415-522-0100

Reported Value
$115M
Q2 2025
Positions
6
Filings on Record
34
2019–present window
Filed
Aug 14, 2025
original filing

Summary

Venbio Partners LLC reported $115M in U.S.-listed holdings across 6 positions for Q2 2025.

The portfolio is heavily concentrated: Pharvaris N V alone accounts for 65.8% of reported value.

Compared with Q1 2025, the fund opened 1 new position and exited 2.

Portfolio Metrics

Turnover
+10.4%
vs prior filed quarter
Largest Position
+65.8%
Pharvaris N V
New / Exited
1 / 2
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded, with multiple share classes and repeated sub-manager rows for the same issuer combined into one position — the same rule the holdings table uses by default. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q1 ’19: $123MQ1 ’19Q2 ’19: $225MQ3 ’19: $211MQ4 ’19: $233MQ1 ’20: $38MQ1 ’20Q2 ’20: $120MQ3 ’20: $658MQ4 ’20: $1.1BQ1 ’21: $1.1BQ1 ’21Q2 ’21: $847MQ3 ’21: $1.0BQ4 ’21: $555MQ1 ’22: $451MQ1 ’22Q2 ’22: $351MQ3 ’22: $432MQ4 ’22: $323MQ1 ’23: $180MQ1 ’23Q2 ’23: $276MQ3 ’23: $353MQ4 ’23: $667MQ1 ’24: $282MQ1 ’24Q2 ’24: $232MQ3 ’24: $194MQ4 ’24: $171MQ1 ’25: $124MQ1 ’25Q2 ’25: $115MQ3 ’25: $176MQ4 ’25: $216MQ1 ’26: $281MQ1 ’26filingsflow.com

Portfolio Composition

By security type
Other: 65.8%Common Stock: 34.2%
  • Other · 65.8% · $75M
  • Common Stock · 34.2% · $39M

Quarter-over-Quarter Changes full breakdown →

vs Q1 2025 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
LYELLYELL IMMUNOPHARMA INCNEW+473.5K473.5K+$4M$4M
ACELYRIN INCSOLD OUT3.81M0$9M$0
LYELL IMMUNOPHARMA INCSOLD OUT7.10M0$4M$0
ALMSALUMIS INCADDED+1.83M4.62M$3M$14M
ARTVARTIVA BIOTHERAPEUTICS INCHELD50.0K1.15M$2M$2M
PHARVARIS N VHELD+04.29M+$8M$75M
ALXOALX ONCOLOGY HLDGS INCHELD+09.70M$2M$4M
HRMYHARMONY BIOSCIENCES HLDGS INHELD+0489.2K$777,819$15M

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q2 2025

6 positions
#IssuerClass% PortfolioValueShares
1PHARVARIS N VCOM65.78%$75M4.29M
2HRMYHARMONY BIOSCIENCES HLDGS INhistory →COM13.47%$15M489.2K
3ALMSALUMIS INChistory →COM12.08%$14M4.62M
4LYELLYELL IMMUNOPHARMA INChistory →COM NEW3.65%$4M473.5K
5ALXOALX ONCOLOGY HLDGS INChistory →COM3.51%$4M9.70M
6ARTVARTIVA BIOTHERAPEUTICS INChistory →COM1.51%$2M1.15M

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$281M6May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$216M6Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$176M6Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$115M6Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$124M7May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$171M7Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$194M6Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$232M6Aug 14, 202413F-HRchanges · EDGAR ↗
Q1 2024$282M5May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$667M7Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$353M8Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$276M7Aug 14, 202313F-HRchanges · EDGAR ↗
Q1 2023$180M6May 15, 202313F-HRchanges · EDGAR ↗
Q4 2022$323M7Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$432M8Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$351M9Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$451M10May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$555M9Feb 14, 202213F-HRchanges · EDGAR ↗
Q3 2021$1.0B9Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021$847M10Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$1.1B8May 17, 202113F-HRchanges · EDGAR ↗
Q4 2020$1.1B7Feb 16, 202113F-HRchanges · EDGAR ↗
Q3 2020$658M8Nov 16, 202013F-HRchanges · EDGAR ↗
Q2 2020$120M4Aug 14, 202013F-HRchanges · EDGAR ↗
Q1 2020$38M3May 26, 202013F-HRchanges · EDGAR ↗
Q4 2019$233M6May 20, 2020RESTATEMENTchanges · EDGAR ↗
Q3 2019$211M6May 20, 2020RESTATEMENTchanges · EDGAR ↗
Q2 2019$225M6May 20, 2020RESTATEMENTchanges · EDGAR ↗
Q1 2019$123M4May 20, 2020RESTATEMENTchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.