SEC 13F Intelligence

Managers / Q1 2022 · view latest →

venBio Partners LLC

CIK 0001776382 · 1700 OWENS STREET, SUITE 595, SAN FRANCISCO, CA, 94158 · 415-522-0100

Reported Value
$451M
Q1 2022
Positions
10
Filings on Record
34
2019–present window
Filed
May 16, 2022
original filing

Summary

Venbio Partners LLC reported $451M in U.S.-listed holdings across 10 positions for Q1 2022.

The portfolio is heavily concentrated: ALXO alone accounts for 36.3% of reported value.

Compared with Q4 2021, the fund opened 1 new position and exited 0.

Portfolio Metrics

Turnover
+8.9%
vs prior filed quarter
Top-10 Concentration
+100.0%
share of reported value
Largest Position
+36.3%
Alx Oncology

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded, with multiple share classes and repeated sub-manager rows for the same issuer combined into one position — the same rule the holdings table uses by default. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q1 ’19: $123MQ1 ’19Q2 ’19: $225MQ3 ’19: $211MQ4 ’19: $233MQ1 ’20: $38MQ1 ’20Q2 ’20: $120MQ3 ’20: $658MQ4 ’20: $1.1BQ1 ’21: $1.1BQ1 ’21Q2 ’21: $847MQ3 ’21: $1.0BQ4 ’21: $555MQ1 ’22: $451MQ1 ’22Q2 ’22: $351MQ3 ’22: $432MQ4 ’22: $323MQ1 ’23: $180MQ1 ’23Q2 ’23: $276MQ3 ’23: $353MQ4 ’23: $667MQ1 ’24: $282MQ1 ’24Q2 ’24: $232MQ3 ’24: $194MQ4 ’24: $171MQ1 ’25: $124MQ1 ’25Q2 ’25: $115MQ3 ’25: $176MQ4 ’25: $216MQ1 ’26: $281MQ1 ’26filingsflow.com

Portfolio Composition

By security type
Common Stock: 78.8%Other: 21.0%ADR: 0.2%
  • Common Stock · 78.8% · $355M
  • Other · 21.0% · $95M
  • ADR · 0.2% · $808,000

Quarter-over-Quarter Changes full breakdown →

vs Q4 2021 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
CINCOR PHARMA INCNEW+1.98M1.98M+$35M$35M
HRMYHARMONY BIOSCIENCES HLDGS INTRIMMED1.20M1.54M$42M$75M
ALXOALX ONCOLOGY HLDGS INCHELD+09.70M$45M$164M
VENTYX BIOSCIENCES INCHELD+05.01M$32M$68M
AKROAKERO THERAPEUTICS INCHELD+02.17M$15M$31M
ELEVATION ONCOLOGY INCHELD+02.61M$9M$7M
PHARVARIS N VHELD+02.30M+$9M$42M
IMPEL NEUROPHARMA INCHELD+02.76M$6M$18M

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q1 2022

10 positions
#IssuerClass% PortfolioValueShares
1ALXOALX ONCOLOGY HLDGS INChistory →COM36.34%$164M9.70M
2HRMYHARMONY BIOSCIENCES HLDGS INhistory →COM16.66%$75M1.54M
3VENTYX BIOSCIENCES INCCOM15.08%$68M5.01M
4PHARVARIS N VCOM9.26%$42M2.30M
5CINCOR PHARMA INCCOM7.70%$35M1.98M
6AKROAKERO THERAPEUTICS INChistory →COM6.83%$31M2.17M
7IMPEL NEUROPHARMA INCCOM3.90%$18M2.76M
8CHECKMATE PHARMACEUTICALS INCOM2.60%$12M3.67M
9ELEVATION ONCOLOGY INCCOM1.46%$7M2.61M
10VRNAVERONA PHARMA PLCSPONSORED ADS0.18%$808,000161.9K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$281M6May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$216M6Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$176M6Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$115M6Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$124M7May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$171M7Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$194M6Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$232M6Aug 14, 202413F-HRchanges · EDGAR ↗
Q1 2024$282M5May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$667M7Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$353M8Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$276M7Aug 14, 202313F-HRchanges · EDGAR ↗
Q1 2023$180M6May 15, 202313F-HRchanges · EDGAR ↗
Q4 2022$323M7Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$432M8Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$351M9Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$451M10May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$555M9Feb 14, 202213F-HRchanges · EDGAR ↗
Q3 2021$1.0B9Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021$847M10Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$1.1B8May 17, 202113F-HRchanges · EDGAR ↗
Q4 2020$1.1B7Feb 16, 202113F-HRchanges · EDGAR ↗
Q3 2020$658M8Nov 16, 202013F-HRchanges · EDGAR ↗
Q2 2020$120M4Aug 14, 202013F-HRchanges · EDGAR ↗
Q1 2020$38M3May 26, 202013F-HRchanges · EDGAR ↗
Q4 2019$233M6May 20, 2020RESTATEMENTchanges · EDGAR ↗
Q3 2019$211M6May 20, 2020RESTATEMENTchanges · EDGAR ↗
Q2 2019$225M6May 20, 2020RESTATEMENTchanges · EDGAR ↗
Q1 2019$123M4May 20, 2020RESTATEMENTchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.