SEC 13F Intelligence

Managers / Q4 2022 · view latest →

Decheng Capital Management III (Cayman), LLC

CIK 0001747821 · PO BOX 309, UGLAND HOUSE, GRAND CAYMAN, E9, KY1-1104 · 345-949-8066

Reported Value
$267M
Q4 2022
Positions
26
Filings on Record
9
2019–present window
Filed
Feb 9, 2023
original filing

Summary

Decheng Capital Management III (Cayman), LLC reported $267M in U.S.-listed holdings across 26 positions for Q4 2022.

Its largest position, Alpine Immune Sciences, represents 18.5% of the portfolio.

Compared with Q3 2022, the fund opened 2 new positions and exited 2.

Portfolio Metrics

Turnover
+31.9%
vs prior filed quarter
Top-10 Concentration
+80.2%
share of reported value
Largest Position
+18.5%
Alpine Immune Sciences
New / Exited
2 / 2
positions this quarter

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q1 ’22: $326MQ1 ’22Q2 ’22: $264MQ2 ’22Q3 ’22: $276MQ3 ’22Q4 ’22: $267MQ4 ’22Q1 ’23: $248MQ1 ’23Q2 ’23: $319MQ2 ’23Q3 ’23: $313MQ3 ’23Q4 ’23: $300MQ4 ’23filingsflow.com

Portfolio Composition

By security type
Common Stock: 48.5%Other: 33.1%PUBLIC: 18.5%
  • Common Stock · 48.5% · $130M
  • Other · 33.1% · $88M
  • PUBLIC · 18.5% · $49M

Quarter-over-Quarter Changes full breakdown →

vs Q3 2022 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
Alpine Immune Sciences, Inc.NEW+6.71M6.71M+$49M$49M
BeyondSpring Inc.NEW+4.96M4.96M+$9M$9M
NVLSEURAlpine Immune Sciences, Inc.SOLD OUT6.71M0$48M$0
BeyondSpring Inc.SOLD OUT4.96M0$5M$0
AURAAura Biosciences, Inc.ADDED+83.3K293.3K$725,003$3M
ILMNIllumnia, Inc.TRIMMED49.3K80.9K$8M$16M
Prometheus Biosciences, Inc.HELD+0250.0K+$13M$28M
HLTHQCue Health Inc.HELD+08.98M$8M$19M

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q4 2022

26 positions
#IssuerClass% PortfolioValueShares
1Alpine Immune Sciences, Inc.COM18.45%$49M6.71M
2ZNTLZentalis Pharmaceuticals Inc.history →COM13.75%$37M1.82M
3Prometheus Biosciences, Inc.COM10.29%$28M250.0K
4HLTHQCue Health Inc.history →COM6.96%$19M8.98M
5Arcus BioSciences, Inc.COM6.73%$18M869.8K
6ILMNIllumnia, Inc.history →COM6.12%$16M80.9K
7BDQMAlbireo Pharma, Inc.history →COM5.04%$13M623.3K
810x Genomics, Inc.CL A COM4.90%$13M359.6K
9PACBPacific Biosciences of California, Inc.history →COM4.48%$12M1.46M
10BeyondSpring Inc.SHS3.49%$9M4.96M
11Horizon Therapeutics PLCCOM3.36%$9M78.9K
12430Terns Pharmaceuticals, Inc.history →COM2.72%$7M714.3K
13WHWKAadi Bioscience, Inc.history →COM2.53%$7M526.3K
14Mersana Therapeutics, Inc.COM1.98%$5M904.3K
15TORCEURAdicet Bio, Inc.history →COM1.94%$5M580.0K
16EQEquillium Inc.history →COM1.83%$5M4.45M
17AURAAura Biosciences, Inc.history →COM1.15%$3M293.3K
18SGENUSDSeagen Inc.history →COM1.11%$3M23.0K
19Argenx SESHS0.78%$2M5.5K
20AtriCure Inc.COM0.77%$2M46.3K
21Apexigen, Inc.COM0.48%$1M1.89M
22SMFRUSDGeneDx Holdings Corp.COM CL A0.34%$902,5973.42M
23SCYXEURScynexis Inc.COM NEW0.32%$866,666555.6K
24NAUTNautilus Biotechnology, Inc.COM0.20%$540,000300.0K
25Owlet, Inc.COM CL A0.19%$502,295898.4K
26NeuBase Therapeutics, Inc.COM0.07%$190,2001.00M

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q4 2023$300M26Dec 12, 2023RESTATEMENTchanges · EDGAR ↗
Q3 2023$313M27Nov 29, 2023RESTATEMENTchanges · EDGAR ↗
Q2 2023$319M25Jul 28, 202313F-HRchanges · EDGAR ↗
Q1 2023$248M24May 10, 202313F-HRchanges · EDGAR ↗
Q4 2022$267M26Feb 9, 202313F-HRchanges · EDGAR ↗
Q3 2022$276M26Nov 8, 202213F-HRchanges · EDGAR ↗
Q2 2022$264M25Aug 1, 202213F-HRchanges · EDGAR ↗
Q1 2022$326M24May 10, 202213F-HRchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.