SEC 13F Intelligence

Managers / Q1 2026

NEXTBio Capital Management LP

CIK 0002038158 · 500 W 2ND STREET, SUITE 1900, AUSTIN, TX, 78701 · 650-501-0882

Reported Value
$215M
Q1 2026
Positions
24
Filings on Record
2
2019–present window
Filed
May 14, 2026
original filing

Summary

Nextbio Capital Management LP reported $215M in U.S.-listed holdings across 24 positions for Q1 2026.

Its largest position, 430, represents 14.8% of the portfolio.

Compared with Q4 2025, the fund opened 1 new position and exited 0.

Portfolio Metrics

Turnover
+4.4%
vs prior filed quarter
Top-10 Concentration
+71.0%
share of reported value
Largest Position
+14.8%
Terns Pharmaceuticals

Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.

Reported Value by Quarter

13F Reported Value
Q4 ’25: $170MQ4 ’25Q1 ’26: $215MQ1 ’26filingsflow.com

Portfolio Composition

By security type
Common Stock: 81.8%ADR: 13.2%Other: 5.0%
  • Common Stock · 81.8% · $176M
  • ADR · 13.2% · $28M
  • Other · 5.0% · $11M

Quarter-over-Quarter Changes full breakdown →

vs Q4 2025 (amended baseline)

IssuerMoveShare ΔShares nowValue ΔValue now
SMMTSUMMIT THERAPEUTICS INCNEW+89.7K89.7K+$2M$2M
CMPSCOMPASS PATHWAYS PLCADDED+1.27M2.02M+$6M$11M
RYTMRHYTHM PHARMACEUTICALS INCADDED+58.5K126.1K+$4M$11M
GPCRSTRUCTURE THERAPEUTICS INCADDED+38.8K133.2K$146,391$6M
COGTCOGENT BIOSCIENCES INCADDED+35.4K131.2K+$2M$5M
ZBIOZENAS BIOPHARMA INCADDED+104.8K426.7K$3M$8M
CMPXCOMPASS THERAPEUTICS INCTRIMMED265.8K848.2K$1M$4M
IRONDISC MEDICINE INCADDED+9.9K52.7K$30,240$3M

Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.

Holdings — Q1 2026

24 positions
#IssuerClass% PortfolioValueShares
1430TERNS PHARMACEUTICALS INChistory →COM14.80%$32M604.5K
2PTGXPROTAGONIST THERAPEUTICS INChistory →COM11.24%$24M229.6K
3STTKSHATTUCK LABS INChistory →COM9.40%$20M3.15M
4VORVOR BIOPHARMA INChistory →COM NEW8.28%$18M1000.0K
5CMPSCOMPASS PATHWAYS PLChistory →SPONSORED ADS5.19%$11M2.02M
6RYTMRHYTHM PHARMACEUTICALS INChistory →COM5.09%$11M126.1K
7XENEXENON PHARMACEUTICALS INChistory →COM4.95%$11M183.2K
8PVLAPALVELLA THERAPEUTICS INC NEhistory →COM4.79%$10M82.7K
9ZBIOZENAS BIOPHARMA INChistory →COM3.87%$8M426.7K
10IVAINVENTIVA SAhistory →ADS3.44%$7M1.33M
11VSTMVERASTEM INChistory →COM NEW3.22%$7M1.31M
12CRESCENT BIOPHARMA INC.COM3.18%$7M372.9K
13ORICORIC PHARMACEUTICALS INChistory →COM3.08%$7M523.6K
14GPCRSTRUCTURE THERAPEUTICS INChistory →SPONSORED ADS2.98%$6M133.2K
15PCVXVAXCYTE INChistory →COM2.57%$6M95.2K
16COGTCOGENT BIOSCIENCES INChistory →COM2.34%$5M131.2K
17CMPXCOMPASS THERAPEUTICS INChistory →COM2.08%$4M848.2K
18EVMNEVOMMUNE INChistory →COM SHS1.96%$4M184.1K
19OCULIS HOLDING AGORDINARY SHARES1.85%$4M149.6K
20ZLABZAI LAB LTDhistory →ADR1.60%$3M183.4K
21IRONDISC MEDICINE INChistory →COM1.56%$3M52.7K
224XC1KALVISTA PHARMACEUTICALS INChistory →COM1.23%$3M131.8K
23SMMTSUMMIT THERAPEUTICS INCCOM0.79%$2M89.7K
24ACETADICET BIO INCCOM NEW0.50%$1M157.8K

Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$215M24May 14, 202613F-HRchanges · EDGAR ↗
Q4 2025$170M23Feb 13, 202613F-HRchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.