Managers / Q4 2019
VHCP Management II, LLC
CIK 0001602263 · 7 BRYANT PARK, 23RD FLOOR, NEW YORK, NY, 10018 · 650 475 3734
Summary
Vhcp Management II, LLC reported $379M in U.S.-listed holdings across 20 positions for Q4 2019.
The portfolio is heavily concentrated: TXG alone accounts for 35.9% of reported value.
Compared with Q3 2019, the fund opened 8 new positions and exited 9.
Portfolio Metrics
Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded, with multiple share classes and repeated sub-manager rows for the same issuer combined into one position — the same rule the holdings table uses by default. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.
Reported Value by Quarter
Portfolio Composition
- Common Stock · 90.1% · $342M
- Other · 9.9% · $38M
Quarter-over-Quarter Changes full breakdown →
vs Q3 2019 (amended baseline)
| Issuer | Move | Share Δ | Shares now | Value Δ | Value now |
|---|---|---|---|---|---|
| Iveric Bio Inc | NEW | +1.00M | 1.00M | +$9M | $9M |
| Mersana Therapeutics Inc | NEW | +922.5K | 922.5K | +$5M | $5M |
| RLMDRelmada Therapeutics Inc | NEW | +114.9K | 114.9K | +$4M | $4M |
| Adverum Biotechnologies Inc | NEW | +383.6K | 383.6K | +$4M | $4M |
| Forty Seven Inc | NEW | +77.7K | 77.7K | +$3M | $3M |
| Nextcure Inc | NEW | +36.2K | 36.2K | +$2M | $2M |
| Myovant Sciences Ltd | NEW | +76.8K | 76.8K | +$1M | $1M |
| 89Bio Inc | NEW | +41.2K | 41.2K | +$1M | $1M |
Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.
Holdings — Q4 2019
| # | Issuer | Class | % Portfolio | Value ↓ | Shares |
|---|---|---|---|---|---|
| 1 | TXG10X Genomics Inc.history → | COM | 35.91% | $136M | 1.79M |
| 2 | AXSMAxsome Therapeutics Inchistory → | COM | 21.42% | $81M | 786.0K |
| 3 | CNSTConstellation Pharmaceuticalshistory → | COM | 18.64% | $71M | 1.50M |
| 4 | Biohaven Pharmaceuticals | COM | 6.64% | $25M | 462.9K |
| 5 | Shockwave Medical Inc | COM | 3.34% | $13M | 288.8K |
| 6 | Iveric Bio Inc | COM | 2.27% | $9M | 1.00M |
| 7 | Kalvista Pharmaceuticals | COM | 1.72% | $7M | 366.3K |
| 8 | Obseva SA | COM | 1.58% | $6M | 1.57M |
| 9 | Mersana Therapeutics Inc | COM | 1.39% | $5M | 922.5K |
| 10 | SPROSpero Therapeutics Inchistory → | COM | 1.20% | $5M | 474.0K |
| 11 | RLMDRelmada Therapeutics Inchistory → | COM | 1.18% | $4M | 114.9K |
| 12 | Adverum Biotechnologies Inc | COM | 1.16% | $4M | 383.6K |
| 13 | Marinus Pharmaceuticals Inc | COM | 0.85% | $3M | 1.49M |
| 14 | Forty Seven Inc | COM | 0.81% | $3M | 77.7K |
| 15 | MISTMilestone Pharmaceuticals Inc | COM | 0.63% | $2M | 148.6K |
| 16 | Nextcure Inc | COM | 0.54% | $2M | 36.2K |
| 17 | Myovant Sciences Ltd | COM | 0.31% | $1M | 76.8K |
| 18 | 89Bio Inc | COM | 0.29% | $1M | 41.2K |
| 19 | Bellerophon Therapeutics | COM | 0.06% | $230,000 | 659.1K |
| 20 | PTGXProtagonist Therapeutics Inc | COM | 0.06% | $227,000 | 32.2K |
Filing History
13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.