Managers / Q4 2022 · view latest →
First Light Asset Management, LLC
CIK 0001600004 · 3300 EDINBOROUGH WAY, SUITE 201, EDINA, MN, 55435 · 952-831-6500
Summary
First Light Asset Management, LLC reported $1.1B in U.S.-listed holdings across 74 positions for Q4 2022.
Its largest position, MODNEUR, represents 8.6% of the portfolio.
Compared with Q3 2022, the fund opened 23 new positions and exited 20.
Portfolio Metrics
Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.
Reported Value by Quarter
Portfolio Composition
- Common Stock · 82.0% · $883M
- Other · 15.2% · $163M
- ADR · 2.8% · $30M
- ETP · 0.1% · $734,087
Quarter-over-Quarter Changes full breakdown →
vs Q3 2022 (amended baseline)
| Issuer | Move | Share Δ | Shares now | Value Δ | Value now |
|---|---|---|---|---|---|
| HORIZON PHARMA PLC | NEW | +137.1K | 137.1K | +$16M | $16M |
| REPHUSDSOCIETAL CDMO INC | NEW | +8.57M | 8.57M | +$13M | $13M |
| GHGUARDANT HEALTH | NEW | +204.8K | 204.8K | +$6M | $6M |
| ISHARES RUSSELL 2000 GROWTH ETF | NEW | +3.4K | 3.4K | +$734,087 | $734,087 |
| CNCCENTENE CORPORATION | NEW | +5.5K | 5.5K | +$452,777 | $452,777 |
| IARTINTEGRA LIFESCIENCES HOLDINGS CORP | NEW | +7.3K | 7.3K | +$407,124 | $407,124 |
| SNNSMITH & NEPHEW PLC SPONSORED ADR | NEW | +15.1K | 15.1K | +$406,335 | $406,335 |
| ENOVENOVIS CORP | NEW | +7.2K | 7.2K | +$385,505 | $385,505 |
Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.
Holdings — Q4 2022
| # | Issuer | Class | % Portfolio | Value ↓ | Shares |
|---|---|---|---|---|---|
| 1 | MODNEURMODEL N INChistory → | Common Stocks | 8.59% | $93M | 2.28M |
| 2 | PROTHENA CORPORATION PLC | Common Stocks | 8.59% | $93M | 1.54M |
| 3 | RETAEURREATA PHARMACEUTICALS INChistory → | Common Stocks | 7.27% | $78M | 2.06M |
| 4 | ATRCATRICURE INChistory → | Common Stocks | 5.98% | $64M | 1.45M |
| 5 | SPNEUSDSEASPINE HOLDINGS CORPhistory → | Common Stocks | 5.33% | $57M | 6.88M |
| 6 | HALOHALOZYME THERAPEUTICS INChistory → | Common Stocks | 4.88% | $53M | 923.1K |
| 7 | KRYSKRYSTAL BIOTECH INChistory → | Common Stocks | 3.48% | $38M | 473.7K |
| 8 | ATECALPHATEC HOLDINGS INChistory → | Common Stocks | 3.35% | $36M | 2.93M |
| 9 | KARUNA THERAPEUTICS INC | Common Stocks | 3.00% | $32M | 164.6K |
| 10 | SIBNSI-BONE INChistory → | Common Stocks | 2.66% | $29M | 2.11M |
| 11 | KROSKEROS THERAPEUTICS INChistory → | Common Stocks | 2.64% | $28M | 592.4K |
| 12 | PFMTUSDPERFORMANT FINANCIAL CORPORATIONhistory → | Common Stocks | 2.48% | $27M | 7.39M |
| 13 | TNDMTANDEM DIABETES CARE INChistory → | Common Stocks | 2.45% | $26M | 586.1K |
| 14 | CUTREURCUTERA INChistory → | Common Stocks | 2.33% | $25M | 567.1K |
| 15 | NEONEOGENOMICS INChistory → | Common Stocks | 2.30% | $25M | 2.68M |
| 16 | CRNXCRINETICS PHARMACEUTICALS INChistory → | Common Stocks | 2.26% | $24M | 1.33M |
| 17 | AXGNAXOGEN INChistory → | Common Stocks | 2.20% | $24M | 2.37M |
| 18 | FNAUSDPARAGON 28 INChistory → | Common Stocks | 2.19% | $24M | 1.24M |
| 19 | KRMDKORU MEDICAL SYSTEMS INChistory → | Common Stocks | 2.10% | $23M | 6.34M |
| 20 | BCYCBICYCLE THERAPEUTICS PLChistory → | Common Stocks | 1.91% | $21M | 696.4K |
| 21 | PLRXPLIANT THERAPEUTICS INChistory → | Common Stocks | 1.90% | $20M | 1.06M |
| 22 | AXNX*AXONICS MODULATION TECHNOLOGIEShistory → | Common Stocks | 1.80% | $19M | 310.4K |
| 23 | BLUBELLUS HEALTH INChistory → | Common Stocks | 1.80% | $19M | 2.36M |
| 24 | OMCLOMNICELL INChistory → | Common Stocks | 1.61% | $17M | 344.2K |
| 25 | TMDXTRANSMEDICS GROUP INChistory → | Common Stocks | 1.52% | $16M | 265.1K |
| 26 | HORIZON PHARMA PLC | Common Stocks | 1.45% | $16M | 137.1K |
| 27 | IM8NINSMED INChistory → | Common Stocks | 1.39% | $15M | 749.0K |
| 28 | REPHUSDSOCIETAL CDMO INChistory → | Common Stocks | 1.19% | $13M | 8.57M |
| 29 | BMRNBIOMARIN PHARMACEUTICAL INChistory → | Common Stocks | 1.16% | $13M | 120.9K |
| 30 | HCATHEALTH CATALYST INChistory → | Common Stocks | 1.15% | $12M | 1.16M |
| 31 | KIDSORTHOPEDIATRICS CORPhistory → | Common Stocks | 1.12% | $12M | 302.7K |
| 32 | SONENDO INC | Common Stocks | 1.10% | $12M | 4.19M |
| 33 | RAREULTRAGENYX PHARMACEUTICAL INChistory → | Common Stocks | 1.01% | $11M | 234.3K |
| 34 | MXCTGBXMAXCYTE INC | Common Stocks | 0.69% | $7M | 1.37M |
| 35 | PFEPFIZER INC | Common Stocks | 0.67% | $7M | 141.8K |
| 36 | GMABGENMAB AS | Common Stocks | 0.63% | $7M | 160.3K |
| 37 | OPRXOPTIMIZERX CORP | Common Stocks | 0.56% | $6M | 361.3K |
| 38 | ABCAM PLC | Common Stocks | 0.55% | $6M | 379.6K |
| 39 | GHGUARDANT HEALTH | Common Stocks | 0.52% | $6M | 204.8K |
| 40 | CSTLCASTLE BIOSCIENCES INC | Common Stocks | 0.35% | $4M | 161.6K |
| 41 | BVSBIOVENTUS INC | Common Stocks | 0.33% | $4M | 1.38M |
| 42 | AKUMIN INC | Common Stocks | 0.24% | $3M | 3.56M |
| 43 | MIROMATRIX MEDICAL INC | Common Stocks | 0.15% | $2M | 534.7K |
| 44 | SLPSIMULATIONS PLUS INC | Common Stocks | 0.12% | $1M | 35.8K |
| 45 | ISHARES RUSSELL 2000 GROWTH ETF | Common Stocks | 0.07% | $734,087 | 3.4K |
| 46 | HUMHUMANA INC | Common Stocks | 0.04% | $454,825 | 888 |
| 47 | ELVELEVANCE HEALTH INC | Common Stocks | 0.04% | $454,491 | 886 |
| 48 | CNCCENTENE CORPORATION | Common Stocks | 0.04% | $452,777 | 5.5K |
| 49 | IARTINTEGRA LIFESCIENCES HOLDINGS CORP | Common Stocks | 0.04% | $407,124 | 7.3K |
| 50 | SNNSMITH & NEPHEW PLC SPONSORED ADR | Common Stocks | 0.04% | $406,335 | 15.1K |
Filing History
| Quarter | Reported Value | Positions | Filed | Type | Links |
|---|---|---|---|---|---|
| Q1 2026 | $1.1B | 35 | May 15, 2026 | 13F-HR | changes · EDGAR ↗ |
| Q4 2025 | $1.3B | 33 | Feb 17, 2026 | 13F-HR | changes · EDGAR ↗ |
| Q3 2025 | $1.1B | 41 | Nov 14, 2025 | 13F-HR | changes · EDGAR ↗ |
| Q2 2025 | $771M | 38 | Aug 14, 2025 | 13F-HR | changes · EDGAR ↗ |
| Q1 2025 | $876M | 37 | May 15, 2025 | 13F-HR | changes · EDGAR ↗ |
| Q4 2024 | $1.0B | 36 | Feb 14, 2025 | 13F-HR | changes · EDGAR ↗ |
| Q3 2024 | $1.2B | 38 | Nov 14, 2024 | 13F-HR | changes · EDGAR ↗ |
| Q2 2024 | $1.1B | 44 | Aug 14, 2024 | 13F-HR | changes · EDGAR ↗ |
| Q1 2024 | $1.3B | 50 | May 15, 2024 | 13F-HR | changes · EDGAR ↗ |
| Q4 2023 | $1.2B | 75 | Feb 14, 2024 | 13F-HR | changes · EDGAR ↗ |
| Q3 2023 | $1.1B | 75 | Nov 14, 2023 | 13F-HR | changes · EDGAR ↗ |
| Q2 2023 | $1.3B | 79 | Aug 14, 2023 | 13F-HR | changes · EDGAR ↗ |
| Q1 2023 | $1.1B | 74 | May 15, 2023 | 13F-HR | changes · EDGAR ↗ |
| Q4 2022 | $1.1B | 74 | Feb 14, 2023 | 13F-HR | changes · EDGAR ↗ |
| Q3 2022 | $988M | 71 | Nov 14, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q2 2022 | $859M | 71 | Aug 12, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q1 2022 | $1.1B | 75 | May 13, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q4 2021 | $1.4B | 79 | Feb 14, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q3 2021 | $1.5B | 83 | Nov 12, 2021 | 13F-HR | changes · EDGAR ↗ |
| Q2 2021 | $1.7B | 79 | Aug 13, 2021 | 13F-HR | changes · EDGAR ↗ |
| Q1 2021 | $1.5B | 77 | May 17, 2021 | 13F-HR | changes · EDGAR ↗ |
| Q4 2020 | $1.4B | 74 | Feb 16, 2021 | 13F-HR | changes · EDGAR ↗ |
| Q3 2020 | $976M | 60 | Nov 13, 2020 | 13F-HR | changes · EDGAR ↗ |
| Q2 2020 | $858M | 60 | Aug 14, 2020 | 13F-HR | changes · EDGAR ↗ |
| Q1 2020 | $586M | 64 | May 15, 2020 | 13F-HR | changes · EDGAR ↗ |
| Q4 2019 | $782M | 69 | Feb 14, 2020 | 13F-HR | changes · EDGAR ↗ |
| Q3 2019 | $662M | 71 | Nov 14, 2019 | 13F-HR | changes · EDGAR ↗ |
| Q2 2019 | $720M | 73 | Aug 14, 2019 | 13F-HR | changes · EDGAR ↗ |
| Q1 2019 | $770M | 63 | May 15, 2019 | 13F-HR | changes · EDGAR ↗ |
| Q4 2018 | $627M | 59 | Feb 14, 2019 | 13F-HR | changes · EDGAR ↗ |
13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.