SEC 13F Intelligence

Managers / Q4 2021 · view latest →

EcoR1 Capital, LLC

CIK 0001587114 · 357 TEHAMA STREET #3, SAN FRANCISCO, CA, 94103 · 415-448-6534

Reported Value
$3.1B
Q4 2021
Positions
76
Filings on Record
32
2019–present window
Filed
Feb 14, 2022
original filing

Summary

Ecor1 Capital, Llc reported $3.1B in U.S.-listed holdings across 76 positions for Q4 2021.

Its largest position, Prothena, represents 17.8% of the portfolio.

Compared with Q3 2021, the fund opened 20 new positions and exited 16.

Reported Value by Quarter

13F Reported Value
Q4 ’18: $999MQ4 ’18Q1 ’19: $1.1BQ2 ’19: $990MQ3 ’19: $792MQ4 ’19: $1.1BQ4 ’19Q1 ’20: $957MQ2 ’20: $1.4BQ3 ’20: $1.4BQ4 ’20: $1.9BQ4 ’20Q1 ’21: $2.3BQ2 ’21: $2.7BQ3 ’21: $2.9BQ4 ’21: $3.1BQ4 ’21Q1 ’22: $3.2BQ2 ’22: $2.9BQ3 ’22: $3.4BQ4 ’22: $3.29TQ4 ’22Q1 ’23: $3.1BQ2 ’23: $4.1BQ3 ’23: $3.0BQ4 ’23: $3.9BQ4 ’23Q1 ’24: $4.0BQ2 ’24: $3.3BQ3 ’24: $2.9BQ4 ’24: $2.6BQ4 ’24Q1 ’25: $1.7BQ2 ’25: $1.7BQ3 ’25: $2.1BQ4 ’25: $2.2BQ4 ’25Q1 ’26: $2.4Bfilingsflow.com

Portfolio Composition

By security type

Composition data arrives with ticker enrichment.

Quarter-over-Quarter Changes full breakdown →

Holdings — Q4 2021

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Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$2.4B30May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$2.2B30Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$2.1B30Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$1.7B37Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$1.7B46May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$2.6B59Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$2.9B64Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$3.3B55Aug 14, 202413F-HRchanges · EDGAR ↗
Q1 2024$4.0B59May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$3.9B51Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$3.0B51Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$4.1B53Aug 14, 202313F-HRchanges · EDGAR ↗
Q1 2023$3.1B58May 15, 202313F-HRchanges · EDGAR ↗
Q4 2022$3.29T66Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$3.4B76Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$2.9B80Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$3.2B87May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$3.1B76Feb 14, 202213F-HRchanges · EDGAR ↗
Q3 2021$2.9B71Nov 22, 2021RESTATEMENTchanges · EDGAR ↗
Q2 2021$2.7B72Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$2.3B71May 17, 202113F-HRchanges · EDGAR ↗
Q4 2020$1.9B67Feb 16, 202113F-HRchanges · EDGAR ↗
Q3 2020$1.4B50Nov 16, 202013F-HRchanges · EDGAR ↗
Q2 2020$1.4B49Aug 14, 202013F-HRchanges · EDGAR ↗
Q1 2020$957M51May 15, 202013F-HRchanges · EDGAR ↗
Q4 2019$1.1B44Feb 18, 2020RESTATEMENTchanges · EDGAR ↗
Q3 2019$792M41Nov 14, 201913F-HRchanges · EDGAR ↗
Q2 2019$990M40Aug 14, 201913F-HRchanges · EDGAR ↗
Q1 2019$1.1B41May 15, 201913F-HRchanges · EDGAR ↗
Q4 2018$999M54Feb 14, 201913F-HRchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.