SEC 13F Intelligence

Managers / Q2 2022 · view latest →

Flagship Pioneering, LLC

CIK 0001400240 · 55 CAMBRIDGE PARKWAY, SUITE 800E, CAMBRIDGE, MA, 02142 · 617 868-1888

Reported Value
$2.7B
Q2 2022
Positions
33
Filings on Record
30
2019–present window
Filed
Aug 15, 2022
original filing

Summary

Flagship Pioneering, Llc reported $2.7B in U.S.-listed holdings across 33 positions for Q2 2022.

The portfolio is heavily concentrated: MRNA alone accounts for 69.3% of reported value.

Compared with Q1 2022, the fund opened 0 new positions and exited 1.

Reported Value by Quarter

13F Reported Value
Q4 ’18: $2.0BQ4 ’18Q1 ’19: $2.6BQ2 ’19: $2.3BQ3 ’19: $1.8BQ4 ’19: $1.8BQ4 ’19Q1 ’20: $2.1BQ2 ’20: $3.4BQ3 ’20: $3.6BQ4 ’20: $5.5BQ4 ’20Q1 ’21: $6.2BQ2 ’21: $7.8BQ3 ’21: $9.5BQ4 ’21: $6.5BQ4 ’21Q1 ’22: $4.3BQ2 ’22: $2.7BQ3 ’22: $2.4BQ4 ’22: $3.13TQ4 ’22Q1 ’23: $2.6BQ2 ’23: $2.2BQ3 ’23: $1.4BQ4 ’23: $1.3BQ4 ’23Q1 ’24: $1.5BQ2 ’24: $843MQ3 ’24: $592MQ4 ’24: $334MQ4 ’24Q1 ’25: $236MQ2 ’25: $268MQ3 ’25: $293MQ4 ’25: $324MQ4 ’25Q1 ’26: $1.2Bfilingsflow.com

Portfolio Composition

By security type
Common Stock: 90.5%Other: 9.5%
  • Common Stock · 90.5% · $2.4B
  • Other · 9.5% · $252M

Quarter-over-Quarter Changes full breakdown →

Holdings — Q2 2022

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Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$1.2B7May 15, 202613F-HRchanges · EDGAR ↗
Q4 2025$324M6Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$293M8Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$268M8Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$236M8May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$334M10Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$592M12Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$843M12Aug 14, 202413F-HRchanges · EDGAR ↗
Q1 2024$1.5B13May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$1.3B13Feb 14, 202413F-HRchanges · EDGAR ↗
Q3 2023$1.4B18Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$2.2B20Aug 14, 202313F-HRchanges · EDGAR ↗
Q1 2023$2.6B22May 15, 202313F-HRchanges · EDGAR ↗
Q4 2022$3.13T25Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$2.4B35Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$2.7B33Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$4.3B38May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$6.5B38Feb 14, 202213F-HRchanges · EDGAR ↗
Q3 2021$9.5B38Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021$7.8B33Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$6.2B33May 17, 202113F-HRchanges · EDGAR ↗
Q4 2020$5.5B30Feb 16, 202113F-HRchanges · EDGAR ↗
Q3 2020$3.6B17Nov 16, 202013F-HRchanges · EDGAR ↗
Q2 2020$3.4B17Aug 13, 202013F-HRchanges · EDGAR ↗
Q1 2020$2.1B17May 14, 202013F-HRchanges · EDGAR ↗
Q4 2019$1.8B19Feb 13, 202013F-HRchanges · EDGAR ↗
Q3 2019$1.8B20Nov 14, 201913F-HRchanges · EDGAR ↗
Q2 2019$2.3B20Aug 13, 201913F-HRchanges · EDGAR ↗
Q1 2019$2.6B15May 14, 201913F-HRchanges · EDGAR ↗
Q4 2018$2.0B12Feb 13, 201913F-HRchanges · EDGAR ↗

Other Included Managers

This filing reports holdings on behalf of 7 additional managers.

  • Flagship Ventures Fund V General Partner LLC028-18466
  • Flagship Ventures Fund IV General Partner LLC028-17238
  • Noubar Afeyan028-19988
  • Flagship Opportunities Fund I General Partner LLC028-20999
  • Flagship Pioneering Special Opportunities Fund II General Partner LLC028-20997
  • Nutritional Health Fund LTP General Partner LLC028-21001
  • Flagship Pioneering Fund VI General Partner LLC028-20998

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.