Managers / Q3 2019 · view latest →
FRAZIER MANAGEMENT LLC
CIK 0001032165 · 601 UNION ST, SUITE 2110, SEATTLE, WA, 98101 · 2066217200
Summary
Frazier Management LLC reported $320M in U.S.-listed holdings across 19 positions for Q3 2019.
The portfolio is heavily concentrated: ANAB alone accounts for 25.3% of reported value.
Compared with Q2 2019, the fund opened 1 new position and exited 0.
Portfolio Metrics
Methodology: turnover is min(value bought, value sold) ÷ average reported value across the two quarters — value-based, so market moves inflate it slightly versus a share-based measure. Concentration and largest position are shares of the filing’s total reported value, options excluded, with multiple share classes and repeated sub-manager rows for the same issuer combined into one position — the same rule the holdings table uses by default. New/exited counts compare against the prior filed quarter. All figures derive solely from the fund’s 13F filings.
Reported Value by Quarter
Portfolio Composition
- Common Stock · 76.9% · $246M
- Other · 23.1% · $74M
Quarter-over-Quarter Changes full breakdown →
vs Q2 2019 (amended baseline)
| Issuer | Move | Share Δ | Shares now | Value Δ | Value now |
|---|---|---|---|---|---|
| MIRMMIRUM PHARMACEUTICALS INC | NEW | +3.57M | 3.57M | +$36M | $36M |
| SYNLOGIC INC | TRIMMED | −582.8K | 282.6K | −$7M | $647,000 |
| TRANSLATE BIO INC | ADDED | +500.0K | 2.18M | +$377,000 | $22M |
| IOVAIOVANCE BIOTHERAPEUTICS INC | TRIMMED | −437.7K | 1.75M | −$22M | $32M |
| ANABANAPTYSBIO INC | HELD | +0 | 2.32M | −$50M | $81M |
| MILLENDO THERAPEUTICS INC | HELD | +0 | 1.40M | −$6M | $10M |
| GRITSTONE ONCOLOGY INC | HELD | +0 | 2.06M | −$5M | $18M |
| KRYSKRYSTAL BIOTECH INC | HELD | +0 | 895.0K | −$5M | $31M |
Value changes conflate price moves with buying and selling — share changes are the real signal. Share counts are not split-adjusted.
Holdings — Q3 2019
| # | Issuer | Class | % Portfolio | Value ↓ | Shares |
|---|---|---|---|---|---|
| 1 | ANABANAPTYSBIO INChistory → | COM | 25.34% | $81M | 2.32M |
| 2 | MIRMMIRUM PHARMACEUTICALS INChistory → | COM | 11.22% | $36M | 3.57M |
| 3 | IOVAIOVANCE BIOTHERAPEUTICS INChistory → | COM | 9.96% | $32M | 1.75M |
| 4 | KRYSKRYSTAL BIOTECH INChistory → | COM | 9.72% | $31M | 895.0K |
| 5 | COLLCOLLEGIUM PHARMACEUTICAL INChistory → | COM | 6.77% | $22M | 1.89M |
| 6 | TRANSLATE BIO INC | COM | 6.76% | $22M | 2.18M |
| 7 | GRITSTONE ONCOLOGY INC | COM | 5.57% | $18M | 2.06M |
| 8 | ALLENA PHARMACEUTICALS INC | COM | 4.10% | $13M | 3.33M |
| 9 | APTINYX INC | COM | 3.48% | $11M | 3.19M |
| 10 | ALPINE IMMUNE SCIENCES INC | COM | 3.18% | $10M | 2.57M |
| 11 | MILLENDO THERAPEUTICS INC | COM | 3.10% | $10M | 1.40M |
| 12 | ITERUM THERAPEUTICS PLC | SHS | 2.78% | $9M | 1.54M |
| 13 | NABRIVA THERAPEUTICS PLC | SHS | 2.66% | $9M | 4.26M |
| 14 | ENTASIS THERAPEUTICS HLDGS I | COM | 2.52% | $8M | 1.35M |
| 15 | SIERRA ONCOLOGY INC | COM | 0.99% | $3M | 8.11M |
| 16 | CIDARA THERAPEUTICS INC | COM | 0.82% | $3M | 1.31M |
| 17 | KEZAR LIFE SCIENCES INC | COM | 0.48% | $2M | 467.7K |
| 18 | BELLICUM PHARMACEUTICALS INC | COM | 0.35% | $1M | 1.05M |
| 19 | SYNLOGIC INC | COM | 0.20% | $647,000 | 282.6K |
Filing History
| Quarter | Reported Value | Positions | Filed | Type | Links |
|---|---|---|---|---|---|
| Q3 2022 | $0 | 1 | Nov 14, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q2 2022 | $1M | 1 | Aug 10, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q1 2022 | Under review | 2 | May 13, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q4 2021 | $1.3B | 43 | Feb 8, 2022 | 13F-HR | changes · EDGAR ↗ |
| Q3 2021 | $1.2B | 41 | Nov 12, 2021 | 13F-HR | changes · EDGAR ↗ |
| Q2 2021 | $1.1B | 34 | Aug 11, 2021 | 13F-HR | changes · EDGAR ↗ |
| Q1 2021 | $1.2B | 35 | May 12, 2021 | 13F-HR | changes · EDGAR ↗ |
| Q4 2020 | $1.3B | 35 | Feb 11, 2021 | 13F-HR | changes · EDGAR ↗ |
| Q3 2020 | $1.1B | 31 | Nov 12, 2020 | 13F-HR | changes · EDGAR ↗ |
| Q2 2020 | $1.1B | 26 | Aug 4, 2020 | 13F-HR | changes · EDGAR ↗ |
| Q1 2020 | $882M | 25 | May 13, 2020 | 13F-HR | changes · EDGAR ↗ |
| Q4 2019 | $596M | 20 | Feb 13, 2020 | 13F-HR | changes · EDGAR ↗ |
| Q3 2019 | $320M | 19 | Nov 12, 2019 | 13F-HR | changes · EDGAR ↗ |
| Q2 2019 | $390M | 18 | Aug 14, 2019 | 13F-HR | changes · EDGAR ↗ |
| Q1 2019 | $415M | 17 | May 15, 2019 | 13F-HR | changes · EDGAR ↗ |
| Q4 2018 | $388M | 17 | Feb 11, 2019 | 13F-HR | changes · EDGAR ↗ |
13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.