SEC 13F Intelligence

Managers / Q1 2026

PERCEPTIVE ADVISORS LLC

CIK 0001224962 · 51 ASTOR PLACE, 10TH FLOOR, NEW YORK, NY, 10003 · 646-205-5300

Reported Value
$5.1B
Q1 2026
Positions
94
Filings on Record
47
2019–present window
Filed
May 29, 2026
amendment (RESTATEMENT)

Summary

Perceptive Advisors Llc reported $5.1B in U.S.-listed holdings across 94 positions for Q1 2026.

Its largest position, PRAX, represents 12.8% of the portfolio.

Compared with Q4 2025, the fund opened 20 new positions and exited 42.

Reported Value by Quarter

13F Reported Value
Q4 ’18: $2.6BQ4 ’18Q1 ’19: $3.5BQ2 ’19: $4.4BQ3 ’19: $3.7BQ4 ’19: $5.0BQ4 ’19Q1 ’20: $3.8BQ2 ’20: $6.2BQ3 ’20: $6.8BQ4 ’20: $9.3BQ4 ’20Q1 ’21: $7.9BQ2 ’21: $15.4BQ3 ’21: $6.9BQ4 ’21: $6.5BQ4 ’21Q1 ’22: $5.0BQ2 ’22: $3.2BQ3 ’22: $3.4BQ4 ’22: $3.56TQ4 ’22Q1 ’23: $3.4BQ2 ’23: $3.5BQ3 ’23: $3.0BQ4 ’23: $4.5BQ4 ’23Q1 ’24: $5.8BQ2 ’24: $4.2BQ3 ’24: $4.7BQ4 ’24: $3.6BQ4 ’24Q1 ’25: $2.8BQ2 ’25: $2.7BQ3 ’25: $3.5BQ4 ’25: $5.6BQ4 ’25Q1 ’26: $5.1Bfilingsflow.com

Portfolio Composition

By security type

Composition data arrives with ticker enrichment.

Quarter-over-Quarter Changes full breakdown →

Holdings — Q1 2026

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Filing History

QuarterReported ValuePositionsFiledTypeLinks
Q1 2026$5.1B94May 29, 2026RESTATEMENTchanges · EDGAR ↗
Q4 2025$5.6B116Feb 17, 202613F-HRchanges · EDGAR ↗
Q3 2025$3.5B93Nov 14, 202513F-HRchanges · EDGAR ↗
Q2 2025$2.7B85Aug 14, 202513F-HRchanges · EDGAR ↗
Q1 2025$2.8B87May 15, 202513F-HRchanges · EDGAR ↗
Q4 2024$3.6B99Feb 14, 202513F-HRchanges · EDGAR ↗
Q3 2024$4.7B108Nov 14, 202413F-HRchanges · EDGAR ↗
Q2 2024$4.2B110Aug 16, 2024RESTATEMENTchanges · EDGAR ↗
Q1 2024$5.8B112May 15, 202413F-HRchanges · EDGAR ↗
Q4 2023$4.5B101Feb 26, 2024RESTATEMENTchanges · EDGAR ↗
Q3 2023$3.0B97Nov 14, 202313F-HRchanges · EDGAR ↗
Q2 2023$3.5B95Aug 24, 2023RESTATEMENTchanges · EDGAR ↗
Q1 2023$3.4B99May 16, 2023RESTATEMENTchanges · EDGAR ↗
Q4 2022$3.56T96Feb 14, 202313F-HRchanges · EDGAR ↗
Q3 2022$3.4B116Nov 14, 202213F-HRchanges · EDGAR ↗
Q2 2022$3.2B111Aug 15, 202213F-HRchanges · EDGAR ↗
Q1 2022$5.0B135May 16, 202213F-HRchanges · EDGAR ↗
Q4 2021$6.5B145Feb 14, 202213F-HRchanges · EDGAR ↗
Q3 2021$6.9B140Nov 15, 202113F-HRchanges · EDGAR ↗
Q2 2021REVEALED$15.4B299Aug 16, 202113F-HRchanges · EDGAR ↗
Q1 2021$7.9B138May 17, 202113F-HRchanges · EDGAR ↗
Q4 2020$9.3B139Feb 16, 202113F-HRchanges · EDGAR ↗
Q3 2020$6.8B126Nov 16, 202013F-HRchanges · EDGAR ↗
Q2 2020$6.2B125Aug 17, 2020RESTATEMENTchanges · EDGAR ↗
Q1 2020$3.8B113May 18, 2020RESTATEMENTchanges · EDGAR ↗
Q4 2019$5.0B114Feb 19, 2020RESTATEMENTchanges · EDGAR ↗
Q3 2019$3.7B109Nov 14, 201913F-HRchanges · EDGAR ↗
Q2 2019$4.4B104Aug 14, 201913F-HRchanges · EDGAR ↗
Q1 2019$3.5B105May 16, 2019RESTATEMENTchanges · EDGAR ↗
Q4 2018$2.6B101Feb 14, 201913F-HRchanges · EDGAR ↗

13F filings are due up to 45 days after quarter end, so holdings shown here lag the fund’s current book. Source: original SEC filing on EDGAR ↗.